نتایج جستجو برای: midcommissural point mcp

تعداد نتایج: 532825  

2012
Steven Yi Victor Lazzarini Joseph Timoney Damián Keller Marcelo Soares Pimenta

This article discusses the development of theMobile Csound Platform (MCP), a group of related projects that aim to provide support for sound synthesis and processing under various new environments. Csound is itself an established computer music system, derived from the MUSIC N paradigm, which allows various uses and applications through its Application Programming Interface (API). In the articl...

2017
Yoshinobu Takahashi Takahiro Sawada Toshiaki Akahane Yumiko Kawase Hidetoshi Ikeda Keishi Makino Hideo Nakamura Takuichiro Hide Shigetoshi Yano Naoya Hashimoto Hajime Kamada

Whether the poor prognosis of primary central nervous system lymphoma (PCNSL) compared with systemic diffuse large B cell lymphoma (DLBCL) is attributable to the immune privilege of the intracerebral location or to intrinsic differences in the biological characteristics of two types of lymphoma remains unclear. Monocyte chemoattractant protein 1 (MCP-1) is essential to support tumor cell surviv...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2002
James X Rong Joan W Berman Mark B Taubman Edward A Fisher

OBJECTIVE Monocyte chemoattractant protein (MCP)-1 is a proatherogenic factor that is responsible for approximately 60% of plaque macrophages in mouse models of atherosclerosis. We investigated whether lysophosphatidylcholine (LPC), enriched in oxidized low density lipoprotein, can modulate the expression of MCP-1 in arterial wall cells. METHODS AND RESULTS LPC induced a 3-fold increase in MC...

2012
Jamie K. Patel Rachel L. Clifford Karl Deacon Alan J. Knox

Monocyte chemotactic protein-1 (MCP-1) is a member of the CC family of cytokines. It has monocyte and lymphocyte chemotactic activity and stimulates histamine release from basophils. MCP-1 is implicated in the pathogenesis of inflammatory diseases, including asthma. The airway smooth muscle (ASM) layer is thickened in asthma, and the growth factors and cytokines secreted by ASM cells play a rol...

2014
J. N. Pan

Generally, an industrial product has more than one quality characteristic. In order to establish performance measures for evaluating the capability of a multivariate manufacturing process, several multivariate process capability indices have been developed based on the assumption of normality. Quality characteristics of many manufacturing processes in the chemical, pharmaceutical and electronic...

2003
Srinivas Aluri

This paper presents an automated laser sensor system developed for damage detection of an Armored Vehicle Launched Bridge (AVLB) used by the US Army. The paper recounts the five-year effort aimed at developing a condition assessment system for AVLBs. A prototype automated laser sensor system built and tested by CFC-WVU consists of: 1) automated robotic gantry, 2) laser vibrometer, 3) data acqui...

Journal: :Molecular pharmacology 2001
Y L Chang J J Shen B S Wung J J Cheng D L Wang

Wogonin (Wog), an active component of Scutellaria baicalensis, has antioxidant and anti-inflammatory properties. Monocyte chemotactic protein-1 (MCP-1), a potent chemoattractant for monocytes, plays a crucial role in case of early inflammatory responses, including atherosclerosis. In this study, we investigated the effect of Wog on phorbol ester (PMA)-induced MCP-1 expression in human umbilical...

Journal: :The Journal of biological chemistry 2008
Akihide Tanimoto Yoshitaka Murata Ke-Yong Wang Masato Tsutsui Kimitoshi Kohno Yasuyuki Sasaguri

The proinflammatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) is expressed in inflammatory and atherosclerotic lesions. GM-CSF is known to enhance monocytic expression of monocyte chemoattractant protein-1 (MCP-1). However, the molecular mechanism(s) by which GM-CSF up-regulates the MCP-1 expression remains to be clarified. Thus, in this study, we examined our hypothesi...

Journal: :The Journal of Experimental Medicine 1995
J H Gong I Clark-Lewis

Monocyte chemoattractant protein (MCP)-1 analogues were designed to determine the role of the NH2-terminal region in structure and function. The NH2-terminal residue was important for function and receptor binding, as it could not be deleted or extended. However the NH2-terminal pyroglutamate residue of the wild type was not essential as it could be replaced by several other noncyclic amino aci...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2004
Gaia Spinetti Mingyi Wang Robert Monticone Jing Zhang Di Zhao Edward G Lakatta

OBJECTIVE With age, rat arterial walls thicken and vascular smooth muscle cells (VSMCs) exhibit enhanced migration and proliferation. Monocyte chemotactic protein-1 (MCP-1) affects these VSMC properties in vitro. Because arterial angiotensin II, which induces MCP-1 expression, increases with age, we hypothesized that aortic MCP-1 and its receptor CCR2 are also upregulated and affect VSMC proper...

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