نتایج جستجو برای: microbubble

تعداد نتایج: 1643  

2015
Heleen Dewitte Katrien Vanderperren Hendrik Haers Emmelie Stock Luc Duchateau Myriam Hesta Jimmy H. Saunders Stefaan C. De Smedt Ine Lentacker

Microbubbles have shown potential as intralymphatic ultrasound contrast agents while nanoparticle-loaded microbubbles are increasingly investigated for ultrasound-triggered drug and gene delivery. To explore whether mRNA-nanoparticle loaded microbubbles could serve as theranostics for detection of and mRNA transfer to the lymph nodes, we investigate the behavior of unloaded and mRNA-loaded micr...

2000
Kwon-Ha Yoon Chang Guhn Kim Seon-Kwan Juhng Jong Jin Won

The challenge presented to ultrasound imaging technology by the advent of microbubble contrast agents is to create a method that detects the echoes from bubbles in preference to the echoes from tissue. Recent progress in ultrasonography is represented by the development of harmonic and pulse inversion imaging (Fig. 1, 2). Pulse inversion imaging is a newly developed one, which uses the full ban...

Journal: :Biomedical Microdevices 2017

Journal: :Physical review fluids 2021

We present an experimental study of the time-dependent velocity and pressure fields during high-speed microbubble production in a flow-focusing device. Particle tracking velocimetry is used to resolve velocities up 30 m/s at timescales down 100 ns, while numerical simulations give access both gas liquid oscillations.

Journal: :Journal of applied physiology 2011
Martha Sue Carraway Nigel S Key

DECOMPRESSION SICKNESS (DCS) has long been attributed to physical forces exerted by inert gas bubbles that may form in tissues, resulting in vascular occlusion and tissue disruption. Bubble formation occurs when a decrease in ambient pressure exceeds the rate at which soluble inert gas (e.g., nitrogen) can be eliminated from the tissues. Modern theory asserts that many signs and symptoms of DCS...

Journal: :Journal of biomedical optics 2014
Mansik Jeon Wentao Song Elizabeth Huynh Jungho Kim Jeesu Kim Brandon L Helfield Ben Y C Leung David E Goertz Gang Zheng Jungtaek Oh Jonathan F Lovell Chulhong Kim

Ultrasound and photoacoustic imaging are highly complementary modalities since both use ultrasonic detection for operation. Increasingly, photoacoustic and ultrasound have been integrated in terms of hardware instrumentation. To generate a broadly accessible dual-modality contrast agent, we generated microbubbles (a standard ultrasound contrast agent) in a solution of methylene blue (a standard...

2015
E. Carr Everbach D. B. Khismatullin J. T. Flaherty R. A. Roy Damir B. Khismatullin John T. Flaherty Ronald A. Roy

Measurements were undertaken to determine the unknown microbubble-size distribution of a dodecafluoropentane (DDFP) emulsion consisting of 10 droplets/ml in surfactant-stabilized water. The acoustic backscatter of 2-microsecond-duration tonebursts of 30-MHz focused ultrasound was measured from the emulsion as it moved in a coaxial flow. Calibration for the system was accomplished using 3-mm-rad...

Journal: :Bubble Science, Engineering & Technology 2009

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