Gemma Bruera ([email protected]) Katia Cannita ([email protected]) Daniela Di Giacomo ([email protected]) Aude Lamy ([email protected]) Giancarlo Troncone ([email protected]) Antonella Dal Mas ([email protected]) Gino Coletti ([email protected]) Thierry Frebourg ([email protected]) Jean Christophe Sabourin (jean-christophe.sabourin@chu-roue...

Acromesomelic dwarfism is a skeletal dysplasia characterized by disproportionate short stature with predominant involvement of the forearms and hands. Maroteaux et al.{l) first described this form of dwarfism. Over 36 cases have been described till date(2), Of them 3 families consisting of two siblings with definite diagnosis of acromesomelic dwarfism are described(3). Here, we report an Indian...

OBJECTIVE Mucopolysaccharidosis VI (MPS VI; Maroteaux-Lamy syndrome) is a lysosomal storage disease caused by a deficiency of the enzyme N-acetylgalactosamine 4-sulfatase (ASB). This enzyme deficiency leads to a progressive disorder with multiple tissue and organ involvement. The disease is rare and is heterogeneous in its clinical presentation and progression. A potential treatment for this di...

Autophagy, a process for recycling cellular constituents, is normally associated with cell survival and is thought to be beneficial for tumor maintenance. However, in this issue of Cancer Cell, Lamy and colleagues report that multiple myeloma utilizes caspase-10 to restrain autophagy and undergoes autophagic cell death upon its removal or inhibition.

William Jacot ([email protected]) Simon Thezenas ([email protected]) Romain Senal ([email protected]) Cathy Viglianti ([email protected]) Anne-Claire Laberenne ([email protected]) Evelyne Lopez-Crapez ([email protected]) Frédéric Bibeau ([email protected]) Jean-Pierre Bleuse (Jean-Pierre.Bleu...

This note is intended as an introduction to two previous works respectively by Dahmani, Guirardel, Osin, and Cantat, Lamy. We give proofs of a Small Cancellation Theorem for groups acting on simplicial tree. discuss the application group plane polynomial automorphisms over any ground field.

For perfect fields k satisfying [k ¯:k]>2, we construct new normal subgroups of the plane Cremona group and provide an elementary proof its non-simplicity, following melody recent by Blanc, Lamy Zimmermann that rank n over (subfields of) complex numbers is not simple for n≥3.