نتایج جستجو برای: malonyl dichloride

تعداد نتایج: 3527  

Journal: :Analytical and bioanalytical chemistry 2006
Katrin Schütz Markus Persike Reinhold Carle Andreas Schieber

The anthocyanin pattern of artichoke heads (Cynara scolymus L.) has been investigated by high-performance liquid chromatography-electrospray ionization mass spectrometry. For this purpose a suitable extraction and liquid chromatographic method was developed. Besides the main anthocyanins-cyanidin 3,5-diglucoside, cyanidin 3-glucoside, cyanidin 3,5-malonyldiglucoside, cyanidin 3-(3''-malonyl)glu...

Journal: :Hoppe-Seyler's Zeitschrift fur physiologische Chemie 1969
M Sumper C Riepertinger F Lynen

This multienzyme complex behaves during protein fractionation, centrifugation, and electrophoresis as a single protein particle of molecular weight 2.3 x 106 (ref. [ 11). The synthesis of fatty acids requires at least six different enzymatic steps which have been demonstrated with the help of model substrates [2]. After transfer of acetyland malonyl-residues from acetylCoA and malonyl-CoA to th...

2014
Sean Poust Isu Yoon Paul D. Adams Leonard Katz Christopher J. Petzold Jay D. Keasling Beata G. Vertessy

Acyltransferases determine which extender units are incorporated into polyketide and fatty acid products. The ping-pong acyltransferase mechanism utilizes a serine in a conserved GHSxG motif. However, the role of the conserved histidine in this motif is poorly understood. We observed that a histidine to alanine mutation (H640A) in the GHSxG motif of the malonyl-CoA specific yersiniabactin acylt...

Journal: :Acta Crystallographica Section E Structure Reports Online 2008

Journal: :Acta Crystallographica Section E Structure Reports Online 2009

Journal: :Molecular & cellular proteomics : MCP 2015
Gozde Colak Olga Pougovkina Lunzhi Dai Minjia Tan Heleen Te Brinke He Huang Zhongyi Cheng Jeongsoon Park Xuelian Wan Xiaojing Liu Wyatt W Yue Ronald J A Wanders Jason W Locasale David B Lombard Vincent C J de Boer Yingming Zhao

The protein substrates of sirtuin 5-regulated lysine malonylation (Kmal) remain unknown, hindering its functional analysis. In this study, we carried out proteomic screening, which identified 4042 Kmal sites on 1426 proteins in mouse liver and 4943 Kmal sites on 1822 proteins in human fibroblasts. Increased malonyl-CoA levels in malonyl-CoA decarboxylase (MCD)-deficient cells induces Kmal level...

2013
Daniela Albanesi Georgina Reh Marcelo E. Guerin Francis Schaeffer Michel Debarbouille Alejandro Buschiazzo Gustavo E. Schujman Diego de Mendoza Pedro M. Alzari

The biosynthesis of membrane lipids is an essential pathway for virtually all bacteria. Despite its potential importance for the development of novel antibiotics, little is known about the underlying signaling mechanisms that allow bacteria to control their membrane lipid composition within narrow limits. Recent studies disclosed an elaborate feed-forward system that senses the levels of malony...

Journal: :The Journal of clinical investigation 1969
P W Majerus M B Smith G H Clamon

Extracts from human platelets contain the enzymes of de novo fatty acid biosynthesis. The pattern of incorporation of acetate-1-(14)C into fatty acids by intact platelets indicates that these enzymes function in platelets. The level of acetyl-coenzyme A (CoA) carboxylase activity in extracts of platelets from normal subjects is 0.036 +/-0.01 mmumole of malonyl-CoA formed per min per mg of prote...

Journal: :Journal of Petroleum and Mining Engineering 2021

During the production of ethylene dichloride, entrainment catalyst particles out bed is considered a problematic issue that affects conversion hydrogen dichloride and causes repeated unit shut down. In this study effect various operating conditions was measured; fluidizing gas flowrate, parameters, reaction conditions, static design parameters such as internal orifice diameter distributer. A si...

Journal: :Acta Crystallographica Section E Structure Reports Online 2007

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