نتایج جستجو برای: lipofuscin

تعداد نتایج: 879  

Journal: :Biochemistry & Analytical Biochemistry 2018

Journal: :Investigative Opthalmology & Visual Science 2009

Journal: :Marine environmental research 2011
Sabine Schäfer Doris Abele Ellen Weihe Angela Köhler

Female and male individuals of the same species often differ with respect to their susceptibility to toxicant stress. In the present study, sea urchins (Psammechinus miliaris) of both sexes were exposed to high (150 μg L⁻¹) and environmentally relevant (5 μg L⁻¹) concentrations of phenanthrene over 10 days. While food intake was significantly decreased following exposure to 150 μg L⁻¹ phenanthr...

Journal: :Journal of Endocrinology and Thyroid Research 2017

Journal: :Journal of Histochemistry & Cytochemistry 2011

2016
Masao Matsumoto Mika Iseki Masachika Kondo Hisayoshi Shimada Osamu Tsuda Nobuo Fujii Masao KISHIKAWA Mika MATSUMOTO Masachika ISEKI Hisayoshi KONDO Osamu SHIMADA Nobuo TSUDA Hideharu FUJII

Three females in their fifties and five males in their seventies, all of whom had been exposed to the Nagasaki atomic bomb explosion in 1945, were investigated concerning the aging of neurons of the dorsal root ganglia. Through this study dealing with the frequency of neurons with intracytoplasmic pigments, lipofuscin, neuromelanin, eosinophilic granules and neurons free of pigment, no signific...

Journal: :Circulation 2009
Yasutaka Inuzuka Junji Okuda Tsuneaki Kawashima Takao Kato Shinichiro Niizuma Yodo Tamaki Yoshitaka Iwanaga Yuki Yoshida Rie Kosugi Kayo Watanabe-Maeda Yoji Machida Shingo Tsuji Hiroyuki Aburatani Tohru Izumi Toru Kita Tetsuo Shioi

BACKGROUND Heart failure is a typical age-associated disease. Although age-related changes of heart are likely to predispose aged people to heart failure, little is known about the molecular mechanism of cardiac aging. METHODS AND RESULTS We analyzed age-associated changes in murine heart and the manner in which suppression of the p110alpha isoform of phosphoinositide 3-kinase activity modifi...

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