Conjugated linoleic acid (CLA) is one of the most physiological active fatty acids due to its positive effect on  prevention of diseases such as obesity, hyperlipidemia, atherosclerosis and cancer. The aim of this study was to optimize the production of conjugated linoleic acid (CLA)% in  alkali isomerization of safflower oil including  71% linoleic acid (LA)  using response surface methodology...

The free fatty acids (FFAs), linoleic and oleic acids, commonly found in dietary fats can be detected by rats on the basis of gustatory cues following conditioned taste aversion pairings. FFAs depolarize the membrane potential of isolated rat taste receptor cells by inhibiting delayed rectifying potassium channels. This study examined the licking response of rats to sweet, salt, sour, and bitte...

AIMS To investigate how linoleic acid affects conidial production and sclerotial development in a strictly mitotic Aspergillus parasiticus field isolate as related to improving biocompetitivity of atoxigenic Aspergillus species. METHODS AND RESULTS We disrupted A. parasiticusDelta12-oleic acid desaturase gene (odeA) responsible for the conversion of oleic acid to linoleic acid. We examined co...

abstract this experiment was conducted to study the effect of south-west climatic conditions on quantitative and qualitative of fatty acids in dog rose (rosa canina l.) seeds collected from five regions including: semirom (isfahan province), kiar and gerdbishe (charmahal and bakhtiari province), yasuj and meymand (kohgiluye and boyer ahmad province). oil was extracted using soxhlet apparatus; t...

1. Since several lines of evidence have suggested that a diminution of endogenous prostaglandins (PG) may participate in the pathogenesis of a variety of disease states, it would be advantageous to develop therapeutic approaches that augment endogenous prostaglandin synthesis. Since linoleic acid is readily converted to arachidonic acid, we assessed the effects of linoleic acid administration o...

The aim of this study was to determine and compare in situ biohydrogenation (BH) fatty acids in three forms of soybeans and linseed (raw, extruded and roasted). Nylon bags (5×10 cm) containing 4 g of raw, extruded or roasted soybeans or raw, extruded or roasted linseed were incubated in the rumen of fistulated ewes for 4, 8, 12 and 24 hours. Results for linoleic acid (C18:2) showed tha...

Conjugated linoleic acid, better known as CLA, is a fatty acid derived from the required nutrient, linoleic acid. The major structural difference between linoleic acid (an 18 carbon, polyunsaturated fatty acid) and CLA, is that linoleic acid has double bonds at carbons 9 and 12 in a cis configuration (methylene interrupted), while CLA has numerous isomers without methylene interrupted conjugate...

objective(s): mindium laevigatum is an endemic plant of iran and turkey and is widely used as blood purifier, antiasthma and antidyspnea in traditional medicine. chemical composition of volatile materials of the plant and its antioxidant, antimicrobial and cytotoxic activities were reported in this study. materials and methods: simultaneous distillation-extraction (sde) and gc-mass-fid analysis...

Prostaglandin (PG) biosynthesis and kidney function was investigated in 24 adults (23 to 32 yr) during isocaloric formula diet periods, for 2 wk each, providing a linoleic acid supply of 0, 3, 3.5, 4, 6, 8, 13, 17, 18, or 20% of total energy intake. Total protein intake (15 energy %) was constant, as well as 5 g NaCl, 3 g KCl, and 0.6 g cholesterol per 2200 kcal formula diet. The amount of PG m...