Background: Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy of mature B lymphocytes. It is known as a heterogeneous disease with variable therapeutic responses and alternative therapies. Morphological and immunophenotypical evaluation of the biopsy specimens can help diagnose DLBCL. Methods: In the current study, 44 patients were chosen from Shaheed Sadoghi Hospital (2010&nda...

Double-hit B-cell lymphoma is a common designation for a group of tumors characterized by concurrent translocations of MYC and BCL2, BCL6, or other genes. The prognosis of concurrent MYC and BCL6 translocations is not well known. In this study, we assessed rearrangements and expression of MYC, BCL2 and BCL6 in 898 patients with de novo diffuse large B-cell lymphoma treated with standard chemoth...

cutaneous round cell tumors have been classified as mast cell tumor (mct), histiocytoma (hct), lymphosarcoma, undif-ferentiated round cell tumors and occasionally rhabdomyosarcoma in veterinary medicine. an adult cock (gallus domesticus) showing a large solitary integument mass raised on dorso bilateral of cervical part, extending to intercapsular and cranial mid part of the back was referred t...

Note Anaplastic large cell lymphoma can be classified into: 1Primary systemic ALK+ ALCL, 2Primary systemic ALKALCL, 3Primary cutaneous ALCL (see in paragraph Pathology). The 2 first categories are defined according to the involvement (or not) of ALK in fusion proteins with various partners (see below); ALK+ ALCL cases are sometimes called ALK lymphomas, or ALKomas. ALK+ ALCL can be further divi...

Keywords Disease name and synonyms Differential diagnosis Frequency Definition Clinical description Etiology Genetic features Diagnostic methods Staging Prognostic parameters Treatment Survival Keywords References Abstract Primary diffuse large B-cell lymphomas (DLB-CL) are aggressive tumors accounting for approximately 40% of the B-cell malignancies. DLB-CL are commonly composed of a mixture o...

Expert Panel on Radiation Oncology–Lymphoma: Bouthaina S. Dabaja, MD; Ranjana Advani, MD; David C. Hodgson, MD; Sughosh Dhakal, MD; Christopher R. Flowers, MD, MS; Chul S. Ha, MD; Bradford S. Hoppe, MD, MPH; Nancy P. Mendenhall, MD; Monika L. Metzger, MD; John P. Plastaras, MD, PhD; Kenneth B. Roberts, MD; Ronald Shapiro, MD; Sonali M. Smith, MD; Stephanie A. Terezakis, MD; Karen M. Winkfield, ...