نتایج جستجو برای: laboratory male rat

تعداد نتایج: 844409  

Journal: :Blood 1985
Z Rolović N Basara N Stojanović N Suvajdzić V Pavlović-Kentera

The Belgrade laboratory (b/b) rat has a hereditary hypochromic microcytic anemia because of defective transmembrane iron transport into erythroblasts. The present study was prompted by our previous work in which we showed that the b/b rat has hypomegakaryocytic thrombocytopenia associated with increased megakaryocyte size. To define the basic mechanism underlying this abnormality in the b/b rat...

2016
Dandan Yu Yali Zhong Xiaoran Li Yaqing Li Xiaoli Li Jing Cao Zhirui Fan Huijie Fan Long Yuan Benling Xu Yuan Yuan Hongquan Zhang Zhenyu Ji Jian-Guo Wen Mingzhi Zhang Jahn M. Nesland Zhenhe Suo

Transcription activator-like effector nucleases (TALENs) are valuable tools for precise genome engineering of laboratory animals. Here we utilized this technique for efficient site-specific gene modification to create a fumarate hydratase (FH) gene knockout rat model, in which there was an 11 base-pair deletion in the first exon of the FH gene in 111 rats. 18 live-born targeted mutation offspri...

Journal: :cell journal 0
alireza alizadeh zeinab taleb bita ebrahimi vahid esmaeili abdolhossein shaverdi javad nasr

objective: although key roles for dietary vitamin e (vite) and fatty acid (fa) in fertility have been confirmed, limited data are available on the effects of vite alone, or a constant level of vite supplemented by dietary omega-6 and omega-3 fas in combination on male reproduction. consequently in this paper, the effects of vite, sunflower oil, fish oil and their combination on rat sperm were i...

2015
Ann Arbor

Figure Legend: Figure 1 Bone Fibrous osteodystrophy in a male F344/N rat from a chronic study. There is replacement of bone by fibrous connective tissue. Figure 2 Bone Fibrous osteodystrophy in a male F344/N rat from a chronic study (same animal as in Figure 1). There is replacement of cortical bone by fibrous connective tissue. Figure 3 Bone Fibrous osteodystrophy in a male F344/N rat from a c...

2015

Figure Legend: Figure 1 Skeletal muscle Necrosis in a male F344/N rat from a chronic study. This cross section of skeletal muscle exhibits an extensive, highly fragmented and vacuolated collection of muscle fibers; some are hypereosinophilic, and others are pale. Figure 2 Skeletal muscle Necrosis in a male F344/N rat from a chronic study. Dystrophic mineralization has affected several necrotic ...

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