Acid hydrolysis revealed the constituent amino acids of brevistin as follows: aspartic acid (D-form 2, L-form 1), L-threonine (1), glycine (1), sum of L-valine and L-isoleucine (1), [L-phenylalanine (1), L-tryptophan (1), and 2, 4-diaminobutyric acid (D-form 1, L-form 1). The constituent fatty acid was elucidated to be anteisononanoic acid by gas chromatography-mass spectrometry. A lactone link...

Studies concerning the identity of the serine and threonine deaminases have been carried out in several laboratories. Wood and Gunsalus (1949) employing a partially purified system extracted from Escherichia coli suggested that both serine and threonine are deaminated by the same enzyme. Similarly, studies with Neurospora indicate that these amino acids are deaminated by one enzyme (Yanofsky, 1...