Ketamine in subanesthetic doses became popular as a recreational drug for its strong, quickly achievable antidepressant effect and short-acting, well-tolerated psychotomimetic (hallucinogenic dissociative) effect. Numerous cases of genitourinary system dysfunction associated with ketamine use have been reported. We describe case ketamine-use-related symptoms 23-year-old man who was found to acu...

The Ketamine Stun is simply the addition of a small dose of ketamine to any injectable chemical restraint technique. I initially developed the Ketamine Stun technique in the early 1990's to cover my limited cat handling abilities. My first exposure to camelid patients came when I left equine practice to teach at Ohio State. The recalcitrant behavior they frequently exhibited quickly led to expe...

BACKGROUND Depression and anxiety are prevalent and undertreated in patients receiving hospice care. Standard antidepressants do not work rapidly or often enough to benefit most of these patients. Ketamine has many properties that make it an interesting candidate for rapidly treating depression and anxiety in patients receiving hospice care. To test this hypothesis, a 28-day, open-label, proof-...

BACKGROUND Ketamine rapidly reduces thoughts of suicide in patients with treatment-resistant depression who are at low risk for suicide. However, the extent to which ketamine reduces thoughts of suicide in depressed patients with current suicidal ideation remains unknown. METHODS Between April 2012 and October 2013, 14 outpatients with DSM-IV-diagnosed major depressive disorder were recruited...

Patients taking high-dose opioids chronically for tumor-related or neuropathic pain may develop pain that is refractory to opioids. One option for control of such pain is the use of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine. We describe a case of opioid-refractory pain that responded to a low-dose IV infusion of ketamine in the inpatient setting. The patient was then successf...

Summary Ketamine is a racemic mixture of two enantiomers, R- and S-ketamine [1]. The primarily used as anaesthestic agent. In low or sub anaesthetic doses, ketamine has potent analgesic properties, it been effectively either primary adjuvant in varieties pain syndromes burn dressings children [2]. this case report, we illustrate the effectiveness oral controlling during wound dressing an adult ...

background: ketamine is the only anesthetic agent that leads to an increase of blood pressure and heart rate by activation of sympathetic nervous system. however, there is a controversy about this effect of ketamine especially if used in small dosage. we proposed to evaluate the hemodynamic effect of small dose of ketamine during phacoemulsification. methods: one hundred patients of asa physica...

The purpose of this study was to investigate the renal protective efficacy propofol, ketamine, and ketofol in an ischemia/reperfusion injury (IRI) model experimentally induced rats. Thirty-five male Sprague-Dawley rats were randomly assigned into five groups: sham (Group 1), control 2), ketamine 3), propofol 4), 5). Following administration intramuscular hydrochloride anesthesia, left hilum exp...

conclusions although almost all of the < 1 year-old children could be sedated with midazolam alone, most of the > 1 year-old children required ketamine or general anesthesia. performing circumcision when children are less than 1 year old decreases the risk of complications due to anesthesia and lowers the costs compared with performing the procedure on older children. results a total of 603 chi...

BACKGROUND In order to determine whether a combination of guaiphenesin, ketamine and xylazine can induce safe and satisfactory anaesthesia in mules undergoing field castration, eight healthy adult intact male mules were employed. They were premedicated with intravenous (IV) xylazine (1.3 mg/kg); an additional dose of xylazine (0.3 mg/kg IV) was administered in case of inadequate depth of sedati...