When using phiX174 RFI DNA as a template, invitro, E. coli RNA polymerase synthesizes four major purine triphosphate-containing 5' end sequences. RNase A digests of alpha(32)P labeled RNA were further digested with spleen exonuclease to remove the bulk of the oligonucleotides with 5' hydroxyls and then chromatographed on DEAE cellulose to resolve the remaining 5' terminal oligonucleotides. By a...

An elegant synthesis of newer aminobenzylated mannich bases (6a to 6j) is described in the present study. These were synthesized by reacting aromatic aldehydes, cyclic secondary amines and a reagent with active hydrogen atom such as Urea in the presence of hydrochloric acid. The constituents of the newly synthesized compounds have been established on the basis of their physical and spectral dat...

We demonstrate the deliberate activation or inhibition of invitro angiogenesis using functional peptide coated gold nanoparticles. The peptides, anchored to oligo-ethylene glycol capped gold nanospheres, were designed to selectively interact with cell receptors responsible for activation or inhibition of angiogenesis. The functional particles are shown to influence significantly the extent and ...

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The aim of this study was to determine the Lactobacillus plantarum isolated from soy milk, the antimicrobial activity of the bacteriocin produced by the isolate against the pathogenic bacteria and antibiotic resistance of these isolates.The identity of the culture was based on characteristics of the strains of Lactobacillus spp. as presented in Bergey’s Manual of Determinative Bacteriology, car...

A total of 50 cases bovine clinical mastitis in Tripoli were subjected to microbiological examination. Thirty-five bacterial isolates obtained and further identified by using the biochemical tests. Staphylococcus spp. (36%) was predominant causative organism, then E. coli (24%) Streptococcus (6%) Additionally, twelve caused nonbacterial agents. The bacteria tested for their in-vitro susceptibil...