نتایج جستجو برای: intravenous sodium valproate

تعداد نتایج: 264072  

Background and Objectives: Epilepsy is a chronic neurological disorder that requires long treatment with less side effects. Therefore, this study aimed to determine the effect of sodium valproate and electrical stimulation of the brain with low frequency (LFS) on the motor activity of male rat during hippocampus rapid kindling. Material and Methods: In this experimental study, 56 male adult ra...

Journal: :Seizure 2007
Sanjay N. Mandhane Keerthikumar Aavula T. Rajamannar

The intravenous pentylenetetrazol (i.v.PTZ) seizure test provides threshold dose for induction of seizures in individual animals. In the present study, the i.v. and s.c.PTZ seizure models in mice were compared for seizure pattern, intra- and interanimal variability. Anticonvulsant activities of several antiepileptic drugs (AEDs) at non-ataxic dose levels were evaluated in the PTZ and maximal el...

2018
Massimiliano Buoli Marta Serati Andrea Botturi A Carlo Altamura

Valproate is an effective anti-epileptic and mood stabilizer drug, but its prescription may be complicated by the development of thrombocytopenia. The purpose of the present manuscript is to provide a critical overview about the risk of thrombocytopenia during treatment with valproate. A search of the main database sources has been conducted to identify relevant papers about the topic. In the s...

Journal: :The Canadian Journal of Psychiatry 2001

2016

Purpose: If corticosteroids are an effective abortive migraine treatment in the non-pregnant adult population, corticosteroids could be trialed for acute, severe migraine treatment in pregnancy. The purpose of this evidence-based practice review was to determine the efficacy of DXM at achieving acute severe migraine resolution in non-pregnant adult migraineurs. Methods: PubMed and Academic Sear...

Journal: :Japanese Journal of Hospital Pharmacy 1985

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