OBJECTIVE We wanted to assess the need for surgical excising papillary lesions of the breast that were diagnosed upon sonographically guided 14-gauge core needle biopsy. MATERIALS AND METHODS Sixty-nine women (age range: 25-74 years, mean age: 51.7 years) with 69 papillary lesions (4.9%) were diagnosed and followed after performing sonographically guided 14-gauge core needle biopsies. Surgica...

In cancer patients and in those at high risk, systemic exposure to agents for therapy or prevention is accompanied by undesirable side effects. We hypothesized that it is possible to prevent and treat breast cancer by introducing anticancer agents into the mammary ductal network. Here, we show the efficacy of intraductally administered anticancer agents 4-hydroxytamoxifen and pegylated liposoma...

Intraductal papillary neoplasm of the bile duct (IPNB) is a variant type of the bile duct carcinoma characterized by intraductal growth. IPNB is also recognized as a precursor of invasive carcinoma. We describe herein an extremely rare case of IPNB arising from the cystic duct. A 68-year-old man was admitted to our hospital for investigation of epigastralgia and abnormal levels of biliary tract...

Context Intraductal Papillary Mucinous Neoplasm of the pancreas is an increasingly diagnosed neoplasm that rarely penetrates adjacent organs. Case report A sixty-year-old asymptomatic male was seen for evaluation of iron deficiency anemia. Patient was found to have a mucin secreting tumor during esophagogastroduodenoscopy. Computed tomography scan showed an enlarged pancreas with numerous focal...

background: improvements in imaging techniques has led to an increase in the number of diagnosed pancreatic cysts. although most of the detected cases are benign, a significant percentage of them are malignant or are potentially malignant. currently, endosonography, and analysis of cyst morphology, fine needle aspiration (fna) of the cyst contents, and measurement of the amylase and carcinoembr...

BACKGROUND A 57-year old woman had only unilateral milky dischardge of the right breast. Clinical and mammography findings were normal. CASE PRESENTATION Cytological diagnosis of intraductal papilloma was established which was galactographically confitmed and patient underwent to surgery. Ductulolobular segmentectomy was made. Histopathologically beside intraductal papilloma numerous single d...

One of the difficulties that translational scientists encounter in evaluating agents to prevent breast cancer is the assessment of efficacy in real time. Classically, one evaluates chemopreventive efficacy based on whether the intervention leads to a lower number of cancers in the treatment than in the control group(s), but these studies require a large sample size and/or take years to complete...

Like other forms of laparoscopic surgery, laparoscopic pancreaticoduodenectomy (Lap-PD) is a minimally invasive procedure that can greatly reduce bleeding during surgery. We performed Lap-PD for a case of intraductal papillary mucinous neoplasm. To remove the resected tissue from the body, we made a small incision directly above the line of transection of the distal pancreas (the cut stump). Th...

BACKGROUND Increasing interest in the intraductal approach to the breast has necessitated revisiting the anatomy of the breast. METHODS Using six different complementary in vivo and in vitro approaches, the authors determined the number, distribution, and anatomic properties of the ductal systems of the breast, which extend from the nipple orifices to the terminal duct lobular units. RESULT...