This work introduces a new technology for electron intensity modulation, which uses small area island blocks within the collimating aperture and small area island apertures in the collimating insert. Due to multiple Coulomb scattering, electrons contribute dose under island blocks and lateral to island apertures. By selecting appropriate lateral positions and diameters of a set of island blocks...

Radiotherapy is a treatment of carcinogenic tumors using ionising radiation and the improvement radiotherapy techniques has been conducted to protection healthy tissues. Recent implementations have employed static fields with small dimensions. The interests for this work were fields, used in modern such as Stereotactic Radiation Therapy (SRS) Intensity Modulated (IMRT).

background: the monte carlo method is the most accurate method for simulation of radiation therapy equipment. the linear accelerators are currently the most widely used machines in radiation therapy centers. methods: in this work, a monte carlo modelling of the siemens oncor linear accelerator in 6 mv and 18 mv beams was performed. the results of simulation were validated by measurements in wat...

BACKGROUND Intensity-modulated radiation therapy (IMRT) uses solid compensators or multileaf collimators to modulate the intensity of radiation in each field, delivering highly conformal dose distributions. This technique allows treating volumes with concave shapes when the target is close to a critical structure. The movement of multileaf collimator under computer control can modulate the dose...

Radiation therapy is subject to uncertainties that need to be accounted for when determining a suitable treatment plan for a cancer patient. For lung and liver tumors, the presence of breathing motion during treatment is a challenge to the effective and reliable delivery of the radiation. In this paper, we build a model of motion uncertainty using probability density functions that describe bre...

In intensity-modulated radiation therapy (IMRT) not only is the shape of the beam controlled, but combinations of open and closed multileaf collimators modulate the intensity as well. In this paper, we offer a mixed integer programming approach which allows optimization over beamlet fluence weights as well as beam and couch angles. Computational strategies, including a constraint and column gen...

3 Sammanfattning (Swedish) 4 Original papers 5 Abbreviations 6