Before the advent of the influenza A(H1N1)pdm virus in 2009, the information available about the clinical manifestations and prognosis of influenza in immunosuppressed patients was scarce. With the 2009 pandemic, knowledge of the behavior, severity and importance of antiviral therapy for influenza A infection in immunocompromised hosts has increased considerably. The aim of the present manuscri...

: Coronavirus disease 2019 (COVID-19) pandemic gripped the globe. SARS-CoV-2 is highly infectious and susceptible to all populations. Immunosuppressed patients have greater risk for opportunistic infections. However, understanding regarding biological characteristics of in immunosuppressed remains unclear. Herein, we present a case prolonged shedding liver transplant patient with COVID-19. A 61...

We report the case of a 59 year old woman who presented to the emergency room with a four day history of abdominal pain worsening over the last 24 hours. She had previously been diagnosed with Alport’s syndrome and had undergone an unrelated donor renal transplant in August 2001. She was on several immunosuppressants. There was some evidence of peritoneal signs on physical exam. Plain film X-ra...

Merkel cell carcinoma is an uncommon neuroendocrine carcinoma with a rising incidence and an aggressive behavior. It predominantly occurs in older patients, with onset occurring at a mean age of 75-80 years. Recognized risk factors are ultraviolet sunlight exposure, immunosuppression, and, more recently, Merkel cell polyomavirus. We report a case of Merkel cell carcinoma in a young HIV positive...

The Phylum Microsporidia comprises >1,200 species, only 15 of which are known to infect humans, including the genera Trachipleistophora, Pleistophora, and Brachiola. We report an infection by Tubulinosema sp. in an immunosuppressed patient.

Using both traditional methods and broad-range 18S ribosomal DNA (rDNA) polymerase chain reaction, we examined 2 cases of lethal cestodiasis, in which the disease agent had been poorly identified or misidentified. In one case, involving a patient with AIDS, we identified the human dwarf tapeworm, Hymenolepis nana, as a cause of aberrant metastatic larval disease. In the second case with similar...

Aplastic anemia is an immunosuppressed illness that difficult to treat. Planning for future renal transplantation in such individuals makes the situation more challenging since we must continue immunosuppression necessary a stable allograft while also ensuring aplastic remission.

Three rapid assay techniques (latex agglutination, laser nephelometry, and EMIT enzyme immunoassay) have been evaluated for serial monitoring of the serum C reactive protein (CRP) concentration in immunosuppressed patients with fever. Radial immunodiffusion assay was used as a reference method. Latex agglutination reliably distinguished between normal and raised serum CRP concentrations. Enzyme...

Recent case reports have shown that hepatitis E virus (HEV) infection can cause chronic hepatitis in immunosuppressed or immunocompromised patients. A 37-year-old woman suffered from prolonged elevation of aminotransferases after chemotherapy for Burkitt's lymphoma and was diagnosed with chronic hepatitis E due to a transfusion during chemotherapy. After an 8-month administration of ribavirin, ...

Introduction The impact of pharmacological immunosuppression (IS) on COVID-19 outcomes is unclear. This study aimed at investigating the hospitalised patients undergoing IS and focussed length hospital stay, admission to intensive care unit (ICU) mortality. Material methods Patients admitted public hospitals in Southern Switzerland with SARS-CoV-2 infection (n = 442) were prospectively included...