OBJECTIVE To report an unusual involvement of focal distal muscles but not proximal muscles in a patient with hypokalemic periodic paralysis (hypoPP). CLINICAL PRESENTATION AND INTERVENTION A middle-aged woman presented with episodic weakness of the bilateral thumbs lasting for 2 years. Hypokalemia and a left adrenal mass were subsequently found. Her weakness subsided after surgical removal o...

OBJECTIVE To examine whether sodium pump activity plays a part in the pathogenesis of thyrotoxic periodic paralysis. DESIGN Measurement of platelet sodium-potassium ATPase and in vivo sodium pump activities in healthy subjects and thyrotoxic subjects with and without paralysis. SETTING University hospital in Hong Kong. SUBJECTS 21 healthy subjects, 23 untreated thyrotoxic subjects, 13 unt...

Complications of carbon monoxide poisoning include peripheral neuropathy, which is usually confined to the lower extremities. We report a case of carbon monoxide-associated neuropathy resulting in unilateral diaphragmatic paralysis. Possible mechanisms of injury are described.

OBJECTIVE To evaluate exercise test responses in hypokalaemic periodic paralysis (HPP), to determine its value as a diagnostic tool and the factors that could affect the responses. METHODS 22 subjects were studied from two families with HPP caused by R528H mutation, four patients with thyrotoxic periodic paralysis, 15 normal controls, and four controls with hyperthyroidism. All family members...