The COVID-19 pandemic has put a strain on the NHS secondary to unprecedented number of acute admissions requiring high-dependency unit (HDU) and intensive care (ITU) support due respiratory failure sequela hypercoagulability. long-term complications pneumonia are

Coronavirus disease (COVID-19) can induce coagulopathy at the base of sepsis-induced coagulopathy (SIC), which is an important cause of death in these patients. Cytokine storm causes imbalance in coagulation and fibrinolytic system. A combination of hypercoagulability state, decrease or inhibition of fibrinolysis and endotheliopathy causes thromboembolic events. Underlying diseases such as diab...

R udolf Virchow, the brilliant 19th century pathologist, was the first to recognize that blood clots in the pulmonary artery originate as venous thrombi. He stated: “The detachment of larger or smaller fragments from the end of the softening thrombus which are carried along by the current of blood and driven into remote vessels. This gives rise to the very frequent process on which I have besto...

EditorÐAs the in¯uence of i.v. ¯uids on the coagulation system is of importance and also sustains the discussion on optimal ¯uid therapy, we would like to comment on the results reported by Ng and colleagues 1 and the suggestions presented in the accompanying editorial. 2 The study design chosen by Ng and colleagues 1 to investigate coagulation and haemodilution might eliminate the in¯uence of ...