نتایج جستجو برای: hydroxypropyl methyl cellulose
تعداد نتایج: 140860 فیلتر نتایج به سال:
A series of (R)-N-Cbz-2-alkyl-2-amino-3-hydroxypropyl acetates was prepared by enzymatic acetylation of NCbz-2-alkyl-2-aminopropane-1,3-diols with immobilized lipoprotein lipase from Pseudomonas sp. in up to 98% enantiomeric excess (ee). Enantiodivergent oxidation of (R)-N-Cbz-2-alkyl-2-amino-3-hydroxypropyl acetates readily furnished (R)and (S)-substituted serines ( -benzylserines and -methyls...
In an effort to find a new oral cephalosporin with well-balanced antibacterial spectrum, good oral absorbability and long plasma half-life, a series of oxyimino aminothiazolyl 3-[(E)- or (Z)-N-substituted carbamoyloxy]propenyl cephems was synthesized and evaluated for antibacterial activity and oral absorbability. The substituents of the carbamoyloxy group affected their in vitro activity and b...
The aggregation status of chlorophyll a (Chl a) and the ability of four cyclodextrins, hydroxypropyl-beta-cyclodextrin (HP-beta-CD), hydroxypropyl-gamma-cyclodextrin (HP-gamma-CD), heptakis(2,6-di-O-methyl)-beta-cyclodextrin (DIMEB), and heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin (TRIMEB), to solubilize the pigment in the complete cellular medium RPMI 1640 was estimated by means of UV-Vis a...
oral ph sensitive drug delivery systems are of utmost importance as these systems deliver the drug at specific part of the gastrointestine (gi) as per the ph of gi, resulting in improved patient therapeutic efficacy and compliance. the ph range of fluids in various segments of the gi tract may provide environmental stimuli for drug release. the aim of this study was to design buoyant beads cont...
A series of chalcones substituted by a quinoxaline unit at the B-ring were synthesized and tested as inhibitors of breast cancer resistance protein-mediated mitoxantrone efflux. These compounds appeared more efficient than analogs containing other B-ring substituents such as 2-naphthyl or 3,4-methylenedioxyphenyl while an intermediate inhibitory activity was obtained with a 1-naphthyl group. In...
Pravastatin sodium is available for oral administration as 10 mg, 20 mg, 40 mg, and 80 mg tablets. Inactive ingredients include: colloidal silicon dioxide, crospovidone, hydroxypropyl methylcellulose, magnesium stearate, mannitol, meglumine, microcrystalline cellulose and starch. The 10 mg, 20 mg and 80 mg tablets also contain D&C Yellow No 10 Aluminium Lake and the 40 mg tablet also contains D...
DifI'..tial scanning calorimetry (~ and dynamic ~-,!jCaJ thermal analysis (DMTA) were used to characterize the morphology of eolv81t cast hydroXYPl'Opyl ceUuloee (Hpc) films. DSC r-.lta windicative of a aemicryltaUine mat«ial with a melt at 220°C and a ,tran8itioo at 19°C (T1). althoucb an 8dditiCXlal _t wu MIumted by a baseline inftectioo at about ~C (Tt). Cc pcx1din, relaxatiMS wfound by DMTA...
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