BACKGROUND BDNF gene polymorphism impacts human motor cortex function and plasticity. OBJECTIVE/HYPOTHESIS Using transcranial magnetic stimulation (TMS), we investigated whether BDNF polymorphism influences cortical plastic changes in acute stroke. METHODS Twenty patients were recruited within 10 days of their first-ever ischemic stroke and genotyped for BDNF polymorphism. Blinded to the la...

In upper brachial plexus birth injury, rotational balance of the glenohumeral joint is frequently affected and contracture in medial rotation of the arm develops, due to a severe palsy or insufficient recovery of the lateral rotators. Some of these children present with a severe glenohumeral joint contracture in the first months, although regular physiotherapy has been provided, a condition ass...

An isolated small wind turbine emulator based on a separately excited DC motor is developed to evaluate the performance of small wind turbine control strategies. The test rig consists of a 3HP separately excited DC motor coupled to a synchronous generator. A dump load is connected to the generator through a buck-boost converter controlled by a microcontroller. Wind turbine rotor and furling dyn...

Poverty of spontaneous movement, slowed execution and reduced amplitudes of movement (akinesia, brady- and hypokinesia) are cardinal motor manifestations of Parkinson's disease that can be modeled in experimental animals by brain lesions affecting midbrain dopaminergic neurons. Most behavioral investigations in experimental parkinsonism have employed short-term observation windows to assess mot...

In artificial small-molecule machines, molecular motors can be used to perform work on coupled systems by applying a mechanical load—such as strain—that allows for energy transduction. Here, we report how ring strain influences the rotation of rotary motor. Bridging two halves motor with alkyl tethers varying sizes yields macrocycles that constrain motor's movement. Increasing size methylene in...

objective: previous studies showed that grape seed extract (gse) is an excellent natural substance with potent antioxidant effect and free radical scavenger. this study aimed to evaluate the effect of gse on motor dysfunctions and thalamic local electroencephalography (eeg) frequency bands' powers in rats with parkinson's disease (pd). materials and methods: in this study 8 µg 6-hydro...