نتایج جستجو برای: humoral immune responses

تعداد نتایج: 609396  

Journal: :The Onderstepoort journal of veterinary research 1998
L C Bebora P N Nyaga C O Kimoro

The immune responses of two S. gallinarum strains, L46 and CN 180, were compared in 15-week-old cockerels. The humoral and cell-mediated immune responses were assayed by means of the indirect haemagglutination test (IHA) and the macrophage migration inhibition test (MIT), respectively. Birds were vaccinated with the two vaccines, respectively, and bled for sera (for IHA) and cells (for MIT) eve...

2016
Vera Lúcia Costa Vale Marcos da Costa Silva Andréia Pacheco de Souza Soraya Castro Trindade Lília Ferreira de Moura-Costa Ellen Karla Nobre dos Santos-Lima Ivana Lucia de Oliveira Nascimento Hugo Saba Pereira Cardoso Edson de Jesus Marques Bruno Jean Adrien Paule Roberto José Meyer Nascimento

BACKGROUND Corynebacterium pseudotuberculosis is the etiologic agent of caseous lymphadenitis (CL), a chronic disease that affects goats and sheep. CL is characterized by the formation of granulomas in lymph nodes and other organs, such as the lungs and liver. Current knowledge of CL pathogenesis indicates that the induction of humoral and cellular immune responses are fundamental to disease co...

Objectives: The aim of the present study was to investigate immunotoxic effect of safranal (SAF), a main component of Crocus sativus essential oil, using Balb/c mice. Materials and Methods: SAF was administered intraperitoneally at doses of 0.1, 0.5 and 1 ml/kg for 3 weeks. Hystopathological examination of spleen and bone marrow, cellularity of spleen, delayed type of hypersensitivity (DTH) res...

Journal: :Journal of virology 2002
Peter K Hocknell Rebecca D Wiley Xiuqing Wang Thomas G Evans William J Bowers Tomas Hanke Howard J Federoff Stephen Dewhurst

Herpes simplex virus type 1 (HSV-1) infects a wide range of cells, including dendritic cells. Consequently, HSV-1 vectors may be capable of eliciting strong immune responses to vectored antigens. To test this hypothesis, an HSV-1 amplicon plasmid encoding human immunodeficiency virus type 1 gp120 was constructed, and murine immune responses to helper virus-free amplicon preparations derived fro...

Journal: :The British journal of nutrition 1994
J M Pollock T G Rowan J B Dixon S D Carter

Thirty-two calves were studied to determine the effects of level of nutrition (400 and 1000 g (air-dry matter) milk substitute per d) and age at weaning (5, 9 and 13 weeks) on humoral immune responses measured in serum and bronchoalveolar washings (BAW). All calves were immunized with Keyhole limpet haemocyanin (KLH) at 3 weeks of age, and with horse erythrocytes (HRBC) 1 d after weaning. Feedi...

2016
Shahneaz Ali Khan Marion Desclozeaux Courtney Waugh Jon Hanger Jo Loader Volker Gerdts Andrew Potter Adam Polkinghorne Kenneth Beagley Peter Timms

Developing a vaccine against Chlamydia is key to combating widespread mortalities and morbidities associated with this infection in koalas (Phascolarctos cinereus). In previous studies, we have shown that two or three doses of a Recombinant Major Outer Membrane Protein (rMOMP) antigen-based vaccine, combined with immune stimulating complex (ISC) adjuvant, results in strong cellular and humoral ...

Journal: :The Journal of infectious diseases 2015
Lindsey R Baden Jinyan Liu Hualin Li Jennifer A Johnson Stephen R Walsh Jane A Kleinjan Brian A Engelson Lauren Peter Peter Abbink Danny A Milner Kevin L Golden Kyle L Viani Matthew D Stachler Benjamin J Chen Maria G Pau Mo Weijtens Brittany R Carey Caroline A Miller Edith M Swann Mark Wolff Hayley Loblein Michael S Seaman Raphael Dolin Dan H Barouch

BACKGROUND Defining mucosal immune responses and inflammation to candidate human immunodeficiency virus type 1 (HIV-1) vaccines represents a current research priority for the HIV-1 vaccine field. In particular, it is unclear whether intramuscular immunization can elicit immune responses at mucosal surfaces in humans. METHODS In this double-blind, randomized, placebo-controlled clinical trial,...

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