BACKGROUND Aqueous extracts of Tridax procumbens (TP) (Compositae) and Phyllanthus amarus (PA) (Euphorbiaceae) are used in traditional medicine in Ghana to treat malaria. Previous studies have demonstrated the anti-trypanosoma, anti-bacterial and anti-HIV effects of TP and PA. OBJECTIVE To assess the antiplasmodial activity of extracts of TP and PA. METHOD Aqueous extracts of TP and PA were...

INTRODUCTION Tridax procumbens, commonly known as coat buttons or tridax daisy, is a species of flowering plant in the daisy family. It is best known as a widespread weed and pest plant. It is native to the tropical Americas but it has been introduced to tropical, subtropical, and mild temperate regions worldwide. Traditionally, Tridax procumbens has been in use in India for wound healing, as A...

The traditional use of medicinal plants in the management of sexual dysfunctions has a long history. This study investigated testicular dysfunction ameliorative effect of the methanolic roots extracts of Maytenus procumbens and Ozoroa paniculosa in a butanol-induced testicular dysfunction rat model. The rats in respective experimental groups were orally administered with the extract at 50 and 2...

Ayurveda, Siddha, Unani and Folk (Tribal) medicines are the major systems of indigenous medicines. Over three-quarters of the world population relies mainly on plants and plant extracts for health care. Unlike many diseases, which can be attributed to the life style of modern man, asthma is an ancient illness. Mast cells play an important role in some type of allergic reaction because the antib...

The in vivo micronucleus assay was used to examine the anticlastogenic effects of crude extracts of Bridelia ferruginea, Vernonia amygdalina, Tridax procumbens, Ocimum gratissimum, and Lawsonia inermis in Wistar albino rats. Extracts of doses of 100 mg/kg body weight were given to rats in five groups for seven consecutive days followed by a single dose of 2-AAF (0.5 mmol/kg body weight). The ra...

This work deals with the effects of the alcoholic extracts of 15 plants (collected from the northern region of Pakistan) on isolated guinea-pig ileum preparation. Dried powdered plant material was extracted with alcohol. The extract obtained after the removal of the alcohol was triturated with pet-ether (40-60°) and then charcoaled, filtered and dried under vacuum. The isolated guinea-pig ileum...

BACKGROUND The use of herbal plant extracts in wound healing is known through decades, but it is necessary to provide scientific data through reverse pharmacology. OBJECTIVE The aim of the present study is to find the mechanism behind the healing of wounds using in vitro and in vivo assays. MATERIAL AND METHODS The study was designed to determine proliferation and mobilization of fibroblast...

BACKGROUND Ethyl acetate extracts of Launaea procumbens is used for the treatment of liver dysfunction as an herbal medicine in Pakistan. In this study, the protective effects of ethyl acetate extracts were evaluated against CCl4-induced liver injuries in rat. METHODS To examine the protective effects against oxidative stress of carbon tetrachloride in rats, 30 male rats were equally divided ...

BACKGROUND Previous studies of Gynura procumbens (G. procumbens) have shown that partially purified fractions of the leaves are capable of lowering the blood pressure of rats by inhibiting angiotensin-converting enzymic activity and causing vasodilatation. The objectives of this study were therefore to further purify the active compounds that exhibited selective effects on blood vessels, determ...

Gynura procumbens, a medicinal plant locally known as Sambung nyawa, is widely used traditionally in South East Asia as a remedy to alleviate symptoms of various ailments including diabetes mellitus. Previous investigators reported that the ethanol plant extract was hypoglycemic in streptozotocin (STZ)-induced diabetic rats and suggested the blood glucose-reducing effect could be due to G. proc...