The first sequenced genome of a plant, Arabidopsis thaliana, was published ,6 years ago (Arabidopsis Genome Initiative, 2000). Since that time, the complete rice genome (Oryza sativa; Goff et al., 2002; Yu et al., 2002; International Rice Genome Sequencing Project, 2005) and a draft sequence of the poplar genome (Populus trichocarpa; http://genome.jgi-psf.org/Poptr1/ Poptr1.home.html) have also...

The first sequenced genome of a plant, Arabidopsis thaliana, was published ,6 years ago (Arabidopsis Genome Initiative, 2000). Since that time, the complete rice genome (Oryza sativa; Goff et al., 2002; Yu et al., 2002; International Rice Genome Sequencing Project, 2005) and a draft sequence of the poplar genome (Populus trichocarpa; http://genome.jgi-psf.org/Poptr1/ Poptr1.home.html) have also...

Overview Comparative genome sequencing has the greatest impact on biology when the targeted genomes impinge directly on analysis or interpretation of the human genome or the genome of a genetic model system. Comparative genomics may also shed light on the genetic and evolutionary mechanisms that determine genome organization and composition. The most obvious benefit of comparative genomics has ...

Assembling fragments randomly sampled from along a sequence is the basis of whole-genome shotgun sequencing, a technique used to map the DNA of the human and other genomes. We calculate the probability that a random sequence can be recovered from a collection of overlapping fragments. We provide an exact solution for an infinite alphabet and in the case of constant overlaps. For the general pro...

The last decade of decreasing DNA sequencing costs and proliferating sequencing services in core labs and companies has brought the de-novo genome sequencing and assembly of insect species within reach for many entomologists. However, sequence production alone is not enough to generate a high quality reference genome, and in many cases, poor planning can lead to extremely fragmented genome asse...

In response to a mandate from the maize (Zea mays) genetics community, a National Science Foundationsponsored workshop was held in St. Louis on July 2, 2001, to discuss technical approaches for a Maize Genome Sequencing Project. This workshop included academic, governmental, and industrial scientists with expertise in analysis of human, animal, plant, and microbial genomes as well as observers ...