This study was carried out to investigate the effects of Sho-saiko-to (Xiao Chai Hu Tang), a Chinese traditional medicine, on the gastric function including the gastric emptying rate (GER) and intragastric pH in rats. Additionally, the effects of the GER and intragastric pH on tolbutamide absorption after oral administration were examined. The GER measured at 40 min after dosing was reduced to ...

abstract injection of sulpiride (d2 receptor antagonist, antipsychotic drug) into vmn hypothalamus, increased gastric volume secretion and decreased gastric ph. the present study the effect of sch23390 (d1 dopamine receptor antagonist) on the gastric acid secretion and its acidity were studied. 70 rats were divided into 7 groups: two control groups, two sham groups given medicine solvents, a sc...

The gastric precancerous process is evaluated in 1788 participants in a gastroscopy survey in the population of Nariño, Colombia, which has one of the highest gastric cancer incidence rates on record. A detailed histological classification is used, and a hierarchical distribution of lesions is described with the main stages being gland neck hyperplasia, atrophy (gland loss), intestinal metaplas...

The large intact prey ingested by Burmese pythons require considerable processing by the stomach before passage into the small intestine. To investigate the function and cost of gastric digestion and its contribution to postprandial metabolic response for the Burmese python, I examined the rate of gastric digestion, the postprandial profile of gastric pH and the effects of decreasing gastric wo...

BACKGROUND Vitamin C may be protective against gastric cancer though infection with Helicobacter pylori is associated with a reduction in intragastric concentrations of vitamin C. AIMS To examine the effects of H pylori infection, gastric juice pH, the severity and extent of gastric inflammation, and CagA antibody status of the individual on gastric juice and mucosal vitamin C concentrations....

A pH/redox-dual responsive, nanoemulsion-embedded composite hydrogel was proposed to well retain magnesium ions in the highly acidic gastric environment, but efficiently release them neutral and reducing intestinal environment.

Gastro-oesophageal reflux is common in preterm infants, but the role of gastric emptying as a causal factor has not been studied before. Gastric emptying was therefore measured in 19 healthy preterm infants (median gestational age 32 weeks) while concurrently measuring 24 hour lower oesophageal pH, using an antimony pH electrode, positioned manometrically. Real time ultrasonic images of the gas...

The gastric precancerous process is evaluated in 1788 participants in a gastroscopy survey in the population of Nariño,Colombia, which has one of the highest gastric cancer incidence rates on record. A detailed histolÃ3gica!classification is used, and a hierarchical distribution of lesions is described with the main stages being gland neck hyperplasia, atrophy (gland loss), intestinal metaplas...

approximately 20% of caustic ingestions result in some degree of esophageal injury. alkaline materials are the most frequent corrosive materials ingested.     the physical form and ph of ingested materials play a critical role in the site and type of gastrointestinal injury (ph > 12 or ph < 1.5, crystalline drain cleaners). unlike alkaline solutions, strong acids are bitter, burn on contact and...