Thirty previously treated adults with lymphoma received AMSA as single agent therapy. All patients had previously received adriamycin-containing chemotherapy regimens and either failed to respond initially or responded but subsequently relapsed. The dose used was 40 mg/sq m.i.v. daily x3. For patients with compromised marrow reserve or elevated bilirubin, a 25% reduction was used. Ten of 30 pat...

In this article, we examine child welfare caseworkers' housing-related service strategies when they serve culturally similar versus culturally dissimilar clients. Testing hypotheses drawn from representative bureaucracy theory and using data from the second cohort of the National Survey of Child and Adolescent Well-Being, we find that when non-Caucasian caseworkers share the same racial/ethnic ...

This paper discusses the performance evaluation and availability analysis of ammonia synthesis unit of a fertilizer plant. The fertilizer plant is a complex and repairable engineering system comprises of various units viz. shell gasification and carbon recovery, desulphurization, co-shift conversion, decarbonation, nitrogen wash and ammonia synthesis etc. One of the most important functionaries...

SARS (severe acute respiratory syndrome) proved an enormous physical and emotional challenge to frontline health care workers throughout the world in late 2002 through to mid 2003. A large percentage of patients (many being health care workers themselves) became critically ill. Unfortunately, clinicians caring for these individuals did not have the advantage of previous experience or research d...

While the small molecule epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors erlotinib and gefitinib have modest clinical benefit in unselected patients with non-small cell lung cancer after platinum-based chemotherapy, an emerging and potentially more elegant strategy is to move these agents to the frontline setting for select patients. Those with somatic mutations in EGFR respo...

The customer relationship management (CRM) system has been touted as a primary tool for supporting frontline employees’ personalized services tasks. Although a number of studies have highlighted the critical role of CRM systems in organizational performance, the link between CRM systems and individual work performance is still under investigation. In order to fill this research gap, the current...

UNLABELLED Corticosteroids as initial therapy for primary immune thrombocytopenia achieve a low rate of sustained remission. METHODS We prospectively evaluated the efficacy, safety, and response duration of low-dose rituximab plus high-dose dexamethasone as frontline therapy in newly diagnosed primary immune thrombocytopenia patients. One cycle of dexamethasone, 40 mg/d/intravenously for four...

AIM To identify aged care specific work health and safety management issues by applying James Reason's safety culture theory to one residential aged care provider in Australia. METHODS Qualitative, semi-structured interviews with frontline care staff at three residential care facilities - all operated by the same provider - garnered employee perceptions of the safety culture and aged care spe...

Mantle cell lymphoma (MCL) is a rare and aggressive subtype of lymphoma associated with a poor prognosis. Chemotherapy is the mainstay of frontline treatment for patients with this disease. Despite high response rates to combination chemotherapy regimens, the majority of patients relapse within a few years of treatment. Therefore, finding efficacious treatments for relapsed or refractory diseas...

Staff working directly with adults' challenging behaviours in learning disability services need to be very good at what they do. They also need to want to do the job. A theory-practice gap exists, however, between what is known about effective, evidence-based approaches and whether and how these are used in person-centred community services. Many frontline staff working with people with the mos...