In a population-based case-control study of breast cancer in Tianjin, China, involving 300 cases and 300 population controls interviewed during 1985-1986, a number of strong risk factors were identified. Although average age at menarche was late by Western standards in this developing country (14.4 years), it was clearly related to risk. Women with their first menstrual period at age 12 years o...

Breast cancer is the top cancer in women worldwide and its incidence is increasing, particularly in developing countries. In the United Arab Emirates (UAE), many cases are first diagnosed in later stages and at younger age compared to those seen in developed countries. Early detection in order to improve breast cancer outcome and survival remains the cornerstone of breast cancer control. Perfor...

Breast disease most commonly affects females; however, a small percentage of men are also affected. Understandably given its low incidence, awareness of male breast disease is low, particularly among the general population. We searched the Medline database from 1950 onwards using the search terms male, breast, neoplasms and gynaecomastia, and reviewed the conditions associated with male breast ...

OBJECTIVES To explore how children of mothers newly diagnosed with breast cancer perceive their mother's illness and its initial treatment; to contrast their accounts with the mothers' perceptions of their children's knowledge. DESIGN Qualitative interview study with thematic analysis. SETTING Home based interviews with mothers and children in Oxfordshire, England. PARTICIPANTS 37 mothers...

The levels of aetiocholanolone, androsterone, and 17-hydroxycorticosteroids were measured in women without known disease of the breast, in women with benign breast disease, and in women with primary and advanced breast cancer. Statistical analysis showed there was no difference in the excretion of urinary 17-hydroxycorticosteroids in the various groups of patients. Detailed analysis of the aeti...

BACKGROUND We aimed to analyse the morphokinetic features of breast fibrocystic changes (nonproliferative lesions, proliferative lesions without atypia and proliferative lesions with atypia) presenting as a non-mass enhancement (NME)in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) examination. PATIENTS AND METHODS Forty-six patients with histologically proven fibrocystic chan...

Breast cancer is the most common malignant tumor among women of reproductive age and is also the most costly according to European reports. In this context, the aim of the present review is to identify factors that make breast cancer in premenopausal women an epidemiological challenge in developing countries. Epidemiological aspects of breast cancer, including risk factors, early detection meth...

A total of 188 women aged 40-54 with cystic breast disease and 2213 asymptomatic controls were questioned in Edinburgh between 1974 and 1978 concerning marital, reproductive, and menstrual status, history of oral contraception use, history of previous breast complaints, and a family history of breast cancer. Women with a history of breast biopsy were at an increased risk of the disease and thos...

Twenty years ago there was little interest in defining personal breast cancer risk or insight into what to offer women at high risk of breast cancer. This situation has changed markedly, partly because of the discovery of the importance of mutations in predisposing genes for breast cancer and partly because of the growing realisation that there were management options that might reduce the risk...

BACKGROUND Despite the great variety of mammaplasty techniques, outcome assessment remains a challenging issue. OBJECTIVES The authors devised an objective method to evaluate mammary symmetry based on statistical analysis of objective manual breast measurements and validated the method by applying it to results of a randomized controlled trial on the correction of breast asymmetry. METHODS ...