Purpose: The aim of this study was to determine the levels irisin in heart, which is a vital organ, rats different ages and reveal whether Ferula elaeochytris (FE) has an effect on expression irisin. 
 Materials Methods: Our designed six groups, young (4 months), middle age (12 old (24 months) were given FE extract for 8 weeks their control groups. After that heart tissues taken measured b...

Background: Ferula species have shown wide range of pharmacological properties but there is no study on oral safety profile of Ferula persica due to standard toxicology guidelines. Objective: This study aimed to evaluate the acute and subchronic oral toxicity of the alcoholic extract of the aerial parts of Ferula persica to provide its safe dose for long term oral administrations as a possible...

In recent years, there has been much importance placed on finding novel therapeutic agents from F. asafoetida plant and it’s common name is Asafoetida. It is commonly used as a traditional medicine in Iran, Afghanistan and India. It is herbaceous plant of the Umbelliferae family and its root contains oleo gum resin which has many medicinal properties. The resin is solid or semisolid with alliac...