PURPOSE To establish whether the disability in benign epilepsy with centrotemporal spikes (BECTS) is the result of the number of seizures, the anti-epileptic therapy or is an inherent characteristic of the syndrome itself. METHODS Thirty-six children with BECTS were tested for cognitive functions prior to commencing treatment with anti-epileptic drugs, and the findings were compared with thos...

Haglund, Michael M. and Daryl W. Hochman. Furosemide and mannitol suppression of epileptic activity in the human brain. J Neurophysiol 94: 907–918, 2005. First published February 23, 2005; doi:10.1152/jn.00944.2004. Most research on basic mechanisms of epilepsy and the design of new antiepileptic drugs has focused on synaptic transmission or action potential generation. However, a number of lab...

Baller-Gerold syndrome (BGS) is characterized by craniosynostosis and preaxial upper-limb malformations, and it has an autosomal recessive inheritance. Valproate syndrome occurs after exposure to valproic acid in utero, and is characterized by trigonocephaly. Both syndromes can also present with other malformations. Herein, we report a female newborn and her brother who both had a history of fe...

objective: to investigate possible immunological humoral correlates in newly diagnosed adult-onset generalized tonic-clonic epilepsy among iranian patients before and after sodium valproate treatment.   patients and methods: 72 adult patients with newly diagnosed idiopathic generalized tonic-clonic epilepsy were recruited. serum antinuclear antibodies (ana), anti-cardiolipin antibodies (acl), a...

Epilepsy is a condition in which a person has recurrent seizures. The mainstay of treatment for epilepsy remains symptomatic despite the rapid expansion in knowledge of its neurological disabilities. Therapeutic options, both medical , surgical and non medical have been markedly improved over the past decades, resulting in better condition, activities of daily living, and quality of life for ep...

The management of epileptic children has greatly improved during the last 10 years with new methods of investigation, new anticonvulsant drugs, and sometimes neurosurgical procedures, but conduct disorders encountered in epileptic children remain a most intractable problem. In spite of popular beliefs only a small proportion of epileptic children have severe disorders of this type. Henderson (1...

OBJECTIVE There is evidence for the existence of bone disease in epileptic patients. The goal of this study was the comparison of serum levels calcium, alkaline phosphatase (ALKP) and 25-hydroxyvitamin D in ambulatory epileptic children in order to evaluate the bone metabolism in epileptic patients. METHODS In this prospective analytical study 48 ambulatory epileptic children who were treated...