The current state-of-the-art assessment of treatment response in breast cancer is based on the response evaluation criteria in solid tumors (RECIST). RECIST reports on changes in gross morphology and divides response into one of four categories. In this paper we highlight how dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted MRI (DW-MRI) may be able to offer ...

OBJECTIVE To evaluate the reproducibility of a protocol for dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for the pharmacokinetic study of breast tumors. MATERIAL AND METHODS We carried out this prospective study from October 2009 through December 2009. We studied 12 patients with stage ii-iii invasive breast cancer without prior treatment. Our center's research ethics commit...

This paper studies household spending responses to anticipated changes in the consumption tax. To do so, I construct a life-cycle heterogeneous-agent general equilibrium model with durables. The features wedge durable transactions that reflects actual tax system: households pay when buying durables but not receive selling them. There are three main findings. First, baseline reproduces an empiri...

We describe features of the HADES radiographic simulation code. We begin with a discussion of why it is useful to simulate transmission radiography. The capabilities of HADES are described, followed by an application of HADES to a dynamic experiment recently performed at the Los Alamos Neutron Science Center. We describe quantitative comparisons between experimental data and HADES simulations u...

background dynamic contrast-enhanced magnetic resonance imaging (dce - mri) has been widely used in the management of breast cancer, and its diagnostic value in breast imaging has been demonstrated. there have only been a few reports regarding the usefulness of pre-contrast imaging. knowledge about clinically significant findings of preoperative, pre-contrast t1 and t2 mr images will allow more...

OBJECTIVES The purpose of this study was to investigate whether quantification of pulmonary perfusion from dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) yields more reproducible results with data acquired during free breathing than with data from conventional breath-hold measurements. MATERIAL AND METHODS Ten healthy male volunteers underwent 2 imaging sessions at a clinical ...

A new methodology based on tensor algebra that uses a higher order singular value decomposition to perform three-dimensional voxel reconstruction from a series of temporal images obtained using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is proposed. Principal component analysis (PCA) is used to robustly extract the spatial and temporal image features and simultaneously de-no...

An interesting approach has been proposed to differentiate malignant glioneuronal tumors (MGNTs) as a subclass of the WHO grade III and IV malignant gliomas. MGNT histologically resemble any WHO grade III or IV glioma but have a different biological behavior, presenting a survival twice longer as WHO glioblastomas and a lower occurrence of metastases. However, neurofilament protein immunostaini...

PURPOSE Fitting tracer kinetic models using linear methods is much faster than using their nonlinear counterparts, although this comes often at the expense of reduced accuracy and precision. The aim of this study was to derive and compare the performance of the linear compartmental tissue uptake (CTU) model with its nonlinear version with respect to their percentage error and precision. THEOR...

Dear Editor, Primary pure osteosarcoma of the breast is a rare malignant tumour and is histologically indistinguishable from conventional osteosarcoma of the bone and other extraskeletal sites. Being a rare entity that is briefl y reported in the radiology literature, it has some interesting imaging features worthy of discussion. Here we report the novel fi ndings of dynamic contrast-enhanced M...