نتایج جستجو برای: ecm model
تعداد نتایج: 2112477 فیلتر نتایج به سال:
Using a firm-level panel data set I assess whether dynamic models of investment provide an empirically fruitful framework for analyzing tax effects on changes in capital stock. In particular I estimate a one-step error correction model (ECM) complementing the usual estimation of a distributed lag model. A correction term accounts for non-random sample attrition, which has not been considered in...
21 Tissue extracellular matrix provides structural support and creates unique environments 22 for resident cells (4, 27). However, the identities of cells responsible for creating specific ECM 23 components have not been determined. In striated muscle, the identity of these cells becomes 24 important in disease when ECM changes result in fibrosis and subsequent increased tissue 25 stiffness and...
Vascular injury induces extensive alteration to the extracellular matrix (ECM). These changes contribute to lesion formation and promote cell migration and proliferation. To elucidate ECM response to arterial injury, we used real-time polymerase chain reaction monitoring to quantitate the expression levels of 81 genes involved in the synthesis and breakdown of ECM as well as receptors and signa...
Extracellular matrix (ECM) is widely used as an inductive biological scaffold to repair soft tissue after injury by promoting functional site-appropriate remodeling of the implanted material. However, there is a lack of non-invasive analysis methods to monitor the remodeling characteristics of the ECM material after implantation and its biodegradation over time. We describe the use of diamagnet...
While mobile shopping (m-shopping) is convenient in the age of mobile commerce, many people still discontinue their shopping using mobile devices even though they have the experience. Therefore, it is important for the m-shopping providers to understand the determinants of m-shopping continuance. This study extended Expectation-Confirmation Model (ECM) to examine the determinants of m-shopping ...
Focal adhesions (FAs) are integrin-based transmembrane assemblies that connect a cell to its extracellular matrix (ECM). They are mechanosensors through which cells exert actin cytoskeleton-mediated traction forces to sense the ECM stiffness. Interestingly, FAs themselves are dynamic structures that adapt their growth in response to mechanical force. It is unclear how the cell manages the plast...
Enterprise Content Management (ECM) is an emerging concept in Information Systems (IS) research providing the means for an efficient administration of digital content. However, there are lots of obstacles which may face enterprises when adopting ECM. In particular the diligent analysis of an organisation‟s individual content situation often turns out to be a major success factor. However, adequ...
In this paper a hybrid circuit is presented which comprises nanoelectronic resistive switches based on the electrochemical memory effect (ECM) as well as devices from a standard 40nm-CMOS process. A closed ECM device model, which is based on device physics, was used for simulations allowing for a precise prediction of the expected I-V characteristics. The device is used as a non-volatile and/or...
Cell migration on a two-dimensional flat surface has been extensively studied and is generally characterized by a front-protrusion-rear-contraction process. In a three-dimensional (3D) environment, on the other hand, cells adopt multiple migration strategies depending on the cell type and the properties of the extracellular matrix (ECM). By using computer simulations, we find that these migrati...
Tumor-associated macrophages (TAMs) promote tumor development, invasion, and dissemination by various mechanisms. In this study, using an orthotopic colorectal cancer (CRC) model, we found that monocyte-derived TAMs advance tumor development by the remodeling of its extracellular matrix (ECM) composition and structure. Unbiased transcriptomic and proteomic analyses of (a) TAM-abundant and -defi...
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