In the present work, the interaction of three water soluble porphyrins, tetra (p-trimethyle) ammoniumphenyl porphyrin iodide (TAPP) as a cationic porphyrin, tetra sodium meso-tetrakis (p-sulphonatophenyle) porphyrin (TSPP) as an anionic porphyrin and manganese tetrakis (p-sulphonato phenyl)porphinato acetate (MnTSPP) as a metal porphyrin, with DNA have been studied by isothermaltitration microc...

The aim of this work is to present the experimental results in form an algorithm for analyzing modification screen printed electrodes, including possibility its regeneration irreversibly oxidizing biologically active compounds (drugs, DNA and proteins). A protocol was developed quantitative analysis study mechanism drug-DNA interaction by differential pulse voltammetry, following parameters: co...

Aim: 1,4-dihydropyridine derivative, 1-(3-phenyl propyl)-4-(2-(2-hydroxybenzylidene) hydrazone)-1,4-dihydropyridine (abbreviated as DHP) was synthesized potential agent for Alzheimer’s disease which is a progressive neurodegenerative brain disorder affecting millions of elderly people. With this study, the electrochemical properties DHP were investigated and its interaction with DNA analyzed by...