نتایج جستجو برای: diethylcarbamazine
تعداد نتایج: 358 فیلتر نتایج به سال:
To support the global program to eliminate lymphatic filariasis (LF), well-monitored demonstration projects are important for defining the relationship between coverage and reductions in microfilaremia. We are using mass treatment with diethylcarbamazine (DEC) and albendazole in an effort to eliminate LF from Leogane, Haiti. Wuchereria bancrofti microfilaremia prevalence at baseline ranged from...
The purpose of the present study was to determine whether or not the elimination of microfilariae by diethylcarbamazine citrate (DEC) would reduce the side effects of a subsequent course of suramin and thus make it more acceptable and safer in the treatment of onchocerciasis. Fifty-four heavily infected patients with ocular onchocerciasis were treated with an initial 2-week course of DEC, in wh...
We are reporting a case of an eye lesion caused by an adult Brugia malayi. The patient was a 3-year-old Chinese boy from Kemaman District, Terengganu, Peninsular Malaysia. He presented with a one week history of redness and palpebral swelling of his right eye. He claimed that he could see a worm in his right eye beneath the conjunctiva. He had no history of traveling overseas and the family kep...
DEC (diethylcarbamazine)-medicated salt, at a concentration of 0.1 to 0.2 mg per 100 mg, was given to the entire population of Karaikal (119 978) in South India for a 4-year period from 1982. The per capita consumption of DEC in medicated salt was 13.3 grams for the entire period. The prevalence of microfilaraemia declined significantly from 4.5% in 1982 to 0.14% in 1985 and 0.4% in 1993. Vecto...
The full-length cDNA sequence encoding Brugia malayi L3 paramyosin has been isolated by immunoscreening a cDNA library with a mouse antiserum raised against Wuchereria bancrofti L3 infective larvae. A recombinant truncated form of paramyosin was expressed as a glutathione S-transferase fusion protein and used to evaluate humoral responses of adults from a W. bancrofti-endemic area in French Pol...
Filarial nematodes infect more than 150 million people worldwide and are responsible for diseases including elephantiasis, river blindness and tropical pulmonary eosinophilia. Antifilarial agents that can kill all the stages in the life cycle of causative filariae have yet to be developed. Very little effort has been made towards rational drug design, employing knowledge gained from studies of ...
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