Objective(s): Nanosilver is one of the most widely used nanomaterials due to its strong antimicrobial activity. Thus, because of increasing potential for exposure of human to nanosilver, there is an increasing concern about possible side effects of these nanoparticles. In this study, we tested the potential dermal toxicity of nanosilver bandage on serum chemical biomarkers in mice.  Materials a...

There are a large number of workers in the United States, spanning a variety of occupational industries and sectors, who are potentially exposed to chemicals that can be absorbed through the skin. Occupational skin exposures can result in numerous diseases that can adversely affect an individual's health and capacity to perform at work. In general, there are three types of chemical-skin interac...

Objective—To evaluate two diVerent techniques for assessing dermal exposure to 4,4'methylene dianiline (MDA) in a field study. The results were used to test the applicability of a recently proposed quantitative dermal occupational exposure limit (DOEL) for MDA in a workplace scenario. Methods—For two consecutive weeks six workers were monitored for exposure to MDA in a factory that made glass f...

As illustrated in the previous chapter, the human body can be exposed to a variety of toxicants that may be present in various environmental media such as air, soil, water, or food. However, just simply being exposed to these hazardous chemicals does not necessarily translate into a toxicological response. The mammalian body has several inherent defense mechanisms and membrane barriers that ten...

conclusions based on the results of the current study, it was concluded that aloe vera, licorice and mint extracts had synergistic effects on the viability of dermal fibroblasts; in addition, the combination of aloe vera and licorice with either henna or myrtle, and aloe vera and mint with either cedar or ginger resulted in synergistic effects on viability of dermal fibroblasts. the third categ...

A 19-year-old female patient visited our clinic for rhinoplasty. She complained about her low take-off point, which was apparent in profile view, and wanted slight tip projection. She refused additional cartilage harvesting from ears or ribs but consented to the use of homologous tissue, including acellular dermal matrix, for her dorsum and tip. Septoturbinoplasty was performed, and only a very...

BACKGROUND Hazardous chemicals and their metabolites may accumulate in the body following repeated airborne exposures and skin contact. AIMS To estimate the contribution of skin absorption to total body burden of N,N-dimethylformamide (DMF) across a working week in two groups with similar levels of respiratory exposure but dissimilar skin contact. METHODS Twenty five workers in a synthetic ...

p-Methylaminophenol Sulfate is a substituted phenol used as a dye and a photographic developer. In skin absorption studies of radioactive p-aminophenol, as much as 11% of the radioactivity was found in the excreta, viscera, and skin of rats. In subchronic and chronic dermal toxicity studies of hair dyes containing p-Methylaminophenol Sulfate, among other active ingredients, no toxicologically s...