This paper describes the ARGUS prototype, a high-density, low-power supercomputer built from an IXIA network analyzer chassis and load modules. The prototype is configured as a diskless distributed system that is scalable to 128 processors in a single 9U chassis. The entire system has a footprint of 0.25 m2 (2.5 ft2), a volume of 0.09 m3 (3.3 ft3) and maximum power consumption of less than 2200...

Introduction. Just as we have created them, the new social media technologies have shaped every aspect of our societies. Meanwhile, information science has hardly addressed the ways in which these information technologies have shaped humans, and vice-versa. The major reason is the tendency and pressure to adjust (the needs of) humans to the ever changing (information) digital devices. The secon...

The social problem described by Jimmy Reid in 1972 [1] is still prevalent in the UK in the twenty-first century. Many people who are socio-economically disadvantaged do not have the capacity to influence their freedom, and as a consequence, they do not have control over the destiny of their own health. In this chapter we examine how socially disadvantaged people in the UK are at greater risk of...

Approximately 30%-%0% of patients with HER2-positive breast cancer will develop central nervous system (CNS) metastasis. Trastuzumab deruxtecan (T-DXd) is known to have clinically relevant activity in HER2- positive metastatic (MBC) who progressed on prevsious lines treatment. DESTINY-Breast01 and DESTINY-Breast03 highlighted the intracranial response long-lasting clinical T-DXd MBC patients. I...