نتایج جستجو برای: core protein

تعداد نتایج: 1424777  

Journal: :Proceedings of the National Academy of Sciences 1980

Journal: :Proteins 2018
J C Gaines S Acebes A Virrueta M Butler L Regan C S O'Hern

We compare side chain prediction and packing of core and non-core regions of soluble proteins, protein-protein interfaces, and transmembrane proteins. We first identified or created comparable databases of high-resolution crystal structures of these 3 protein classes. We show that the solvent-inaccessible cores of the 3 classes of proteins are equally densely packed. As a result, the side chain...

Journal: :Acta Crystallographica Section A Foundations of Crystallography 2008

Journal: :Oncology reports 2016
Jia-Jia Zhou Zhe Meng Yu Zhou Di Cheng Hui-Lin Ye Quan-Bo Zhou Xiao-Geng Deng Ru-Fu Chen

Hepatitis C virus (HCV) core protein plays an important role in the development of hepatocellular carcinoma. octamer-binding protein 4 (OCT4) is critically essential for the pluripotency and self-renewal of embryonic stem cells. Abnormal expression of OCT4 has been detected in several human solid tumors. However, the relationship between HCV core and OCT4 remains uncertain. In the present study...

Journal: :Journal of virology 2014
Jimena Pérez-Vargas Robert C Vaughan Carolyn Houser Kathryn M Hastie C Cheng Kao Glen R Nemerow

UNLABELLED The structure of adenovirus outer capsid was revealed recently at 3- to 4-Å resolution (V. Reddy, S. Natchiar, P. Stewart, and G. Nemerow, Science 329:1071-1075, 2010, http://dx.doi.org/10.1126/science.1187292); however, precise details on the function and biochemical and structural features for the inner core still are lacking. Protein V is one the most important components of the a...

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