Landslides are a common hazard worldwide that result in major economic, environmental and social impacts. Despite their devastating effects, inventorying existing landslides, often the regions at highest risk of reoccurrence, is challenging, time-consuming, and expensive. Current landslide mapping techniques include field inventorying, photogrammetric approaches, and use of bare-earth (BE) lida...

BACKGROUND AND PURPOSE The Heart of Glass (HEG) receptor binds KRIT1 and functions with KRIT1, CCM2, and PDCD10 in a common signaling pathway required for heart and vascular development. Mutations in KRIT1, CCM2, and PDCD10 also underlie human cerebral cavernous malformation (CCM) and postnatal loss of these genes in the mouse endothelium results in rapid CCM formation. Here, we test the role o...

In the model green alga Chlamydomonas reinhardtii, a carbon-concentrating mechanism (CCM) is induced under low CO2 in the light and comprises active inorganic carbon transport components, carbonic anhydrases, and aggregation of Rubisco in the chloroplast pyrenoid. Previous studies have focused predominantly on asynchronous cultures of cells grown under low versus high CO2. Here, we have investi...

Cerebral cavernous malformations (CCM) are irregularly shaped and enlarged capillaries in the brain that are prone to hemorrhage, resulting in headaches, seizures, strokes and even death in patients. The disease affects up to 0.5% of the population and the inherited form has been linked to mutations in one of three genetic loci, CCM1, CCM2 and CCM3. To understand the pathophysiology underlying ...

The recent rise in unfilled training positions among infectious diseases (ID) fellowship programs nationwide indicates that ID is declining as a career choice among internal medicine residency graduates. Supplementing ID training with training in critical care medicine (CCM) might be a way to regenerate interest in the specialty. Hands-on patient care and higher salaries are obvious attractions...

OBJECTIVES To develop dedicated markup language for clinical contents models (CCM) to facilitate the active use of CCM in electronic health record systems. METHODS Based on analysis of the structure and characteristics of CCM in the clinical domain, we designed extensible markup language (XML) based CCM markup language (CCML) schema manually. RESULTS CCML faithfully reflects CCM in both the...

The penalization method is used to take account of obstacles, such as the limiter, in a tokamak. Because of the magnetic confinement of the plasma in a tokamak, the transport occurs essentially in the direction parallel to the magnetic field lines. We study a 1D nonlinear hyperbolic system as a simplified model of the plasma transport in the area close to the wall. A penalization which cuts the...

In this paper, a Conflict Control Manager (CCM) for a ubiquitous services system is presented to prevent the mode confusion of humans. CCM consists of a lock-based conflict detection module and a D-PRI (dynamic priority)-based conflict resolution. By means of CCM, the mode confusion can drastically be reduced, and, as a result, CCM can assist in designing and implementing a human-centered ubiqu...

Cardiac contractility modulating (CCM) signals delivered by the OPTIMIZER System are being investigated as a treatment for medically refractory heart failure. Previous chronic studies of CCM have excluded patients with prolonged QRS and a cardiac resynchronization therapy (CRT) device. However, symptoms persist in more than 25% of these CRT patients. CCM may offer a therapeutic option for these...

There is strong research evidence that community case management (CCM) programs can significantly reduce mortality. There is less evidence, however, on how to implement CCM effectively either from research or regular program data. We analyzed monitoring data from CCM programs supported by the International Rescue Committee (IRC), covering over 2 million treatments provided from 2004 to 2011 in ...