THIRTY-one patients with histologically diagnosed chronic active hepatitis were followed clinically, biochemically and histologically for a mean of 32.5 months. Nineteen patients were intravenous drug abusers. Eighteen patients showed histological improvement: of these 14 had hepatitis B virus (HBV) associated disease. Thirteen patients were unchanged or worse on repeat biopsy; 5 of these had H...

Background. Information regarding the progression of acute hepatitis B virus (HBV) infection to chronic infection in adults is scarce. Methods. Twenty-five adult patients with acute HBV infection (14 men and 11 women, 18-84 years old), whose clinical features progressed to those of chronic infection (group A) or did not (group B), were studied retrospectively. Results. There were 3 and 22 patie...

Hepatitis B viral infection is usually a self-limiting disease in immunocompetent individuals. Chronic infection can be seen in up to 5% of infected patients. Renal manifestations of chronic HBV infection are usually glomerular. We describe here an uncommon presentation of a patient with chronic HBV infection with very high viral load and rapidly progressive renal failure. Renal biopsy showed f...

UNLABELLED In persons with chronic hepatitis C virus (HCV) infections, superinfection by hepatitis A virus (HAV) or hepatitis B virus (HBV) can cause serious complications, including fulminating hepatitis or increased severity of hepatitis. Therefore, it is important to adequately protect persons with chronic HCV infections by immunization. Suboptimal response to vaccines has been reported in p...

The World Health Organization (WHO) Western Pacific Region with an estimated 160 million chronic hepatitis B virus (HBV) carriers in 2007 bears a significant burden of HBV-related mortality and morbidity.1 Most Member States in the region have an estimated chronic HBV infection proportion of more than 8% in their adult population, which is the highest worldwide.2 The WHO Regional Office for the...

We compared the sensitivity of the polymerase chain-reaction (PCR) assay to that of slot-blot hybridization for detecting hepatitis B virus (HBV) DNA in the serum of 31 patients with chronic hepatitis. Of 14 chronic hepatitis patients positive for both HBV surface and HBV e antigens, 9 were positive for HBV DNA by slot-blot hybridization and all 14 by PCR. Also, of 9 patients positive for HBV s...

Hepatitis B virus (HBV) causes significant global health problems despite the presence of a potential vaccine. HBV chronic cases are increasing rapidly in developing countries like Bangladesh. Here, we report the complete genome sequence of an HBV genotype C strain isolated from a chronic patient identified at an outdoor hospital section.

Results Of the 826 HIP evaluated during the study period, chronic HBV infection was found in 198 HIP (23.97%), chronic HCV infection in 6 HIP (0.73%). Chronic HBVHDV coinfection was detected in 6 HIP (9.37%, of 64 HIP evaluated) and chronic HBV-HCV coinfection in 2 HIP (0.24%). The evolution of chronic HBV infection during the study period was as follows: HBs seroconversion in 8 HIP (4.04%), ch...

Chronic hepatitis C virus (HCV) infection combined with occult hepatitis B virus (HBV) infection has been associated with increased risk of hepatitis, cirrhosis and hepatocellular carcinoma. This study aimed to determine the prevalence of occult HBV infection among Egyptian chronic HCV patients, the genotype and occurrence of surface gene mutations of HBV and the impact of co-infection on early...

BACKGROUND Chronic hepatitis B virus (HBV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide. However, the association of untreated chronic hepatitis B virus (HBV) infection with chronic kidney disease (CKD) remains unclear. METHODS This cohort study used claims data in the Taiwan National Health Insurance Research Database in 1996-2010, in which all dis...