objective(s): stroke poses a crucial risk for mortality and morbidity. our study aimed to investigate the effect of p-coumaric acid on focal cerebral ischemia in rats. material and methods: rats were randomly divided into four groups, namely group i (control rats), group ii (ischemia rats), group iii (6 hr ischemia + p-coumaric acid rats) and group iv (24 hr ischemia + p-coumaric acid rats). ce...

background: cerebral venous-sinus thrombosis is an uncommon form but important cause of stroke, especially in young-aged women. methods: we performed a retrospective descriptive-analytical study in which 124 patients with cerebral venous-sinus thrombosis, who referred to nemazee hospital, shiraz university of medical sciences from january 2000 to march 2008, were included, and their demographic...

Acute stroke from cerebral-artery air embolism is a very rare occurrence during esophagogastroduodenoscopy (EGD). Computed tomography is a quick and reliable method of detecting cerebral air embolism if performed within an appropriate timeframe. We found 20 reported cases of air embolism with EGD in the literature; only seven of those resulted in cerebral air embolus. We report an eighth such c...

BACKGROUND AND PURPOSE Both dementia and stroke are major health problems in Chinese societies. Stroke is a frequent cause of dementia. Only a few studies have been published on poststroke dementia (PSDE), none of which has investigated a consecutive stroke cohort in Asian patient populations. The objective of this study was to examine the prevalence and clinical correlates of PSDE in Chinese s...

Cerebral stroke remains the leading cause of death and disability worldwide as well in Ukraine. After a cerebral stroke, there is an increased risk new (9‒15 % within 1 year), about quarter all are recurrent. Up to 80 recurrent can be avoided through lifestyle modifications (healthy diet, sufficient amount physical activity, normalization body weight, cessation smoking alcohol abuse) control ch...

Highlights . Mechanical thrombectomy is the “gold standard” treatment of patients with large-vessel occlusions. Five randomized trials conducted in 2015 made a significant contribution to development and introduction mechanical into clinical practice. The DAWN DEFUSE-3 have provided new insights pathophysiology ischemic stroke ensured advancement therapeutic field. Abstract Stroke one leading c...

Abbreviations: ACC American College of Cardiology, ACGME Accreditation Council for Graduate Medical Education, ECASS European Cooperative Acute Stroke Study, IA intra-arterial, ICH intracranial hemorrhage, IV intravenous, MCA middle cerebral artery, MELT Middle cerebral artery Embolism Local fibrinolytic intervention Trial, MERCI Mechanical Embolus Removal in Cerebral Ischemia [trial], mRS modi...

A complex bidirectional relation between migraine, mostly migraine with aura (MA), and ischaemic stroke is known. A cerebral infarction can occur during a MA, and MA is a risk factor for ischaemic stroke, particularly in young women. Conversely, cerebral ischaemia can induce MA. Both ischaemic stroke and MA might be consequences of many underlying vascular disorders. Despite the relation betwee...

Introduction: Cerebral ischemia and reperfusion causes physiological and biochemical changes in the neuronal cells that will eventually lead to cell damage. Evidence indicates that exercise reduces the ischemia and reperfusion-induced brain damages in animal models of stroke. In the present study, the effect of exercise preconditioning on brain edema and neurological movement disorders followin...

Pervious studies have shown that pentoxifylline (PTX) has beneficial effects in reduction of stroke and brain trauma injuries in experimental animals. However, there is very little and controversial information about the effect of PTX on brain edema in cerebral ischemia. Therefore, the aim of this study was to determine the effects of different doses of PTX on brain edema and neurological m...