Testosterone is overwhelmingly important in regulating erectile physiology. However, the associated molecular mechanisms are poorly understood. The purpose of this study was to explore the effects and mechanisms of testosterone in erectile dysfunction (ED) in castrated rats. Forty male Sprague-Dawley rats were randomized to four groups (control, sham-operated, castration and castration-with-tes...

Thirty male reindeer; n= 6 bulls (control treatment) and n= 4 steers (castrated males) were used to evaluate the effects of early castration on carcass yield and meat quality attributes. The reindeer were castrated at 2 and 3 months of age, and then slaughtered at 2 and 3 years of age. Live weights and carcass weights were significantly highest in the 3 year old bulls and steers. Dressing perce...

The effect of an indigenous drug, Speman, on the accessory reproductive organs was observed on castrated adult mice and on immature intact mice. The dose related growth of ventral prostate and the systemic increase in the weights as well as the secretions of accessory sex organs of the castrated adults treated with Speman indicated that the drug possessed anabolic-cum-androgen like activity

background: sex steroids and their receptors exist in hippocampus and affect spatial learning and memory. this study was designed to measure testosterone level of ca1 and to assess the effect of spatial learning on its amount in left and right hippocampus of adult male rats. methods: sixteen rats were divided into two intact and castrated groups, and then trained in morris water maze (mwm). ano...

This study investigated adrenal androgens (AA), gonadotropins, and cortisol in castrated and gonad-intact male rhesus macaques from birth through infancy. Blood samples were collected longitudinally from castrated (n = 6; weekly, 1-40 wk) and intact (n = 4; every other week, 1-17 wk) males. Plasma concentrations of AA were determined by liquid chromatography-tandem mass spectrometry, and plasma...

Hypophysial portal blood and peripheral blood were obtained from conscious, unrestrained rams to measure simultaneously the secretion of LHRH and LH in entire rams and rams which had been castrated for 2-15 days (short-term castration) and for 1-6 months (long-term castration). The apparatus for portal blood collection was surgically implanted using a transnasal trans-sphenoidal approach and, 4...

Four experiments were conducted to examine the development of castration-induced behavioral changes, the effects of castration age on pig weight gain, and the efficacy of common analgesics for use in castrated pigs. In Exp. 1, behavioral changes associated with castration of pigs at 1, 5, 10, 15, or 20 d of age were evaluated. Castration caused measurable changes (reduced suckling, reduced stan...

background: the secretion of thyroxin (t4) as the main hormone of thyroid gland is regulated by androgens. the present study aimed to evaluate the effect of testosterone and finasteride administration and castration on serum levels of t4 and to show the effect of this regulation on total body weight, weight of testis, and the weight of prostate. methods: male adult rats (n = 32) were divided in...