Radiological evidence of a mass in the anterior mediastinum may provide a difficult problem in diagnosis. Disorders of the thymus, particularly thymomas, are frequently the cause of such mass lesions. Although modest thymic enlargement occurs in many patients with Graves's disease,' rarely is the enlargement great enough to lead to a clinical diagnostic dilemma.2 We report here two patients wit...

Short title: Antithyroid drugs and birth defects

propylthiouracyl. In the case reported, an early diagnosis could not have been made because the patient had no clinical signs and was being treated with methamizole, with the resultant potential implications. It should be noted that the prevalence of liver parameter changes with the other two thioamides is so low that in a case such as the one reported, if the liver profile is not tested, this ...

BACKGROUND Thyrotoxicosis is both rarer and more severe in children than in adults, rendering management difficult and often unsatisfactory. OBJECTIVE To ascertain outcome in a geographically defined area of Scotland between 1989 and 2014. METHOD Retrospective case note review with follow-up questionnaire to family doctors for patients with Graves' disease and Hashimoto's thyroiditis. RES...

21 Thyroid hormones are essential developmental factors, and Graves’ disease (GD) may 22 severely complicate a pregnancy. This review describes how pregnancy changes the risk of 23 developing GD, how early pregnancy by several mechanisms leads to considerable changes in the 24 results of the thyroid function tests used to diagnose hyperthyroidism, and how these changes may 25 complicate the dia...

1. Conversion of thyroxine into tri-iodothyronine and reverse tri-iodothyronine in intact cells was studied with isolated renal tubules prepared by collagenase digestion. 2. Conversion of thyroxine into tri-iodothyronine and reverse tri-iodothyronine increased progressively for at least 90 min. 3. Studies of tri-iodothyronine production from increasing amounts of thyroxine revealed that the thy...

The Liver as a Site and Source of Cancer G. R. CAMERON, D.SC., M.B., F.R.C.P.,F.R.S. 347 Toxic Reactions After Intravenous Saccharated Iron Oxide in Man J. A. NLSSIM, M.D. 352 Common Varieties of Scalp Ringworm J. M. BEARE, M.D., M.R.C.P ...........................356 Atelectasis as a Complication in Artificial Pneumothorax R. L. SADLER, M.B., D.P.H. 359 Fatal Case of Marrow Aplasia after Treat...

BACKGROUND The rationale for use of drugs during pregnancy requires a careful assessment as in addition to the mother, the health and life of her unborn child is also at stake. Information on the use of drugs during pregnancy is not available in Pakistan. The aim of this study was to evaluate the patterns of drug prescriptions to pregnant women in tertiary care hospitals of Pakistan. METHODS ...

BACKGROUND Amiodarone-induced thyrotoxicosis (AIT) is a difficult management problem about which there are little published data. We examined whether continuing amiodarone or differentiating AIT into 2 subtypes affected outcome. METHODS AND RESULTS The type and duration of antithyroid treatment and response were recorded in a consecutive series of 28 cases. Comparisons were made between those...