The interaction between H(+) extrusion via H(+)-ATPase and Cl(-) conductance was studied in the C11 clone of MDCK cells, akin to the intercalated cells of the collecting duct. Cell pH (pHi) was measured by fluorescence microscopy using the fluorescein-derived probe BCECF-AM. Control recovery rate measured after a 20 mM NH(4)Cl acid pulse was 0.136 +/- 0.008 pH units/min (dpHi/dt) in Na(+) Ringe...

Hardware and software for a high-speed, pulsed-data-acquisition system are described. Data can be obtained via any device attachable to a VXI crate, GPIB controller, or directly via serial or parallel ports. Stepper motors controlled via serial port automate probe movement. LabVIEW and custom C11 modules are used to handle setup, data gathering and processing, and user interface. Experimental p...

This paper reviews the analysis of the threshold autoregressive, smooth threshold autoregressive, and Markov switching autoregressive models from the Bayesian perspective. For each model we start by describing a baseline model and discussing possible extensions and applications. Then we review the choice of prior, inference, tests against the linear hypothesis, and conclude with models selectio...

Thermal expansion of MAX phases along different directions tends to be because the anisotropy hexagonal crystals. Herein, a new Hf2SeC phase was synthesized and confirmed relatively isotropic, coefficients thermal (CTEs) c were determined 9.73 μK−1 10.18 μK−1, respectively. The strong MS bond endowed Hf2SC Zr2SC lower CTEs than those Zr2SeC. relationship between ratio elastic stiffness constant...

This Paper describes a procedure for constructing theory restricted prior distributions for BVAR models. The Bayes Factor, which is obtained without any additional computational effort, can be used to assess the plausibility of the restrictions imposed on the VAR parameter vector by competing DSGE models. In other words, it is possible to rank the amount of abstraction implied by each DSGE mode...

The universal mating hormone α 1 of the virulent plant pathogen Phytophthora has been synthesized in 12 steps and 28 % overall yield. Key CC bond-forming steps involved the use of two lithiation/borylation reactions to couple together enantioenriched building blocks, one of which also set up the stereochemistry of the tertiary alcohol at C11. Detailed analysis showed that the diastereomeric pu...

We show that even in the absence of auxiliary variables, the wellknown Owicki-Gries method for verifying concurrent programs is unsound for weak memory models. By strengthening its non-interference check, however, we obtain OGRA, a program logic that is sound for reasoning about programs in the release-acquire fragment of the C11 memory model. We demonstrate the usefulness of this logic by appl...