نتایج جستجو برای: breast tumor

تعداد نتایج: 635142  

Introdution: Today, the Advantages of radiation therapy by charged particles is indicated for the treatment of cancerous. During the passing of proton beam in the body tissues, secondary particles produce, which penetrate to the body healthy tissues and cause damage. The aim of this research was calculating the Spread out Bragg Peak for covering the breast cancer and investigating arrived dose ...

روشنایی, قدرت اله, صدیقی پاشاکی, عبدالعظیم, فردمال, جواد, مافی, مریم, کرمی, منوچهر,

Background and Objective: Breast cancer is the most common cancer among women. Various factors are associated with survival of patients with breast cancer. The aim of this study was to determine the survival rate of patients with breast cancer who referred to MRI center of Hamadan and to explore its related factors. Materials and Methods: In this historical cohort study, 542 women with breast c...

Journal: :iranian journal of basic medical sciences 0
morteza ghandadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran atieh mohammadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran javad behravan department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran biotechnology research center, mashhad university of medical sciences, mashhad, iran khalil abnous pharmaceutical research center, department of medicinal chemistry, school of pharmacy, mashhad university of medical sciences, mashhad, iran negin haj-ali department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s): acquisition of tnf-α resistance plays role in the onset and growth of malignant tumors. previous studies have demonstrated that mcf-7 cell line and its doxorubicin resistant variant mcf-7/adr are resistant against the cytotoxic effects of tnf-α. in this study, we investigated the role of akt activation in resistance of mcf-7 and mcf-7/adr against tnf-α cytotoxicity. materials and ...

Journal: :iranian journal of basic medical sciences 0
mahnaz nourbakhsh biotechnology research center, mashhad university of medical sciences, mashhad, iran nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran mahmoud reza jaafari nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran hermann lage charite´ campus mitte, institute of pathology, charite´platz 1, d-10117 berlin, germany

objective(s): p-glycoprotein (p-gp) is an efflux protein, the overexpression of which has been associated with multidrug resistance in various cancers. although sirna delivery to reverse p-gp expression may be promising for sensitizing of tumor cells to cytotoxic drugs, the therapeutic use of sirna requires effective carriers that can deliver sirna intracellularly with minimal toxicity on targe...

Phyllodes tumors are biphasic fibroepithelial neoplasms of the breast. While the surgical management of these relatively uncommon tumors has been addressed in the literature, few reports have commented on the surgical approach to tumors greater than ten centimetres in diameter – the giant phyllodes tumor. We report a case of giant breast tumors and discuss the techniques utilized for pre-...

Background: Breast cancer is the most common invasive cancer with high mortality in women all around the world. The present evidence shows that younger patients have poor survival. Thus, the aim of this study was to compare the pathologic characteristics of breast cancer in women younger than 40 years compared with older. Methods: This is a cross-sectional study which contains 681 patients wit...

Journal: :middle east journal of cancer 0
fereshteh mehdipour shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz, iran mahyar malekzadeh shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz, iran abdolrasoul talei department of surgery, school of medicine, shiraz university of medical sciences, shiraz, iran abbas ghaderi shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz, iran

background: interleukin-19, a member of the interleukin-10 family of cytokines, contributes to breast cancer pathogenesis. high interleukin-19 expression in breast tumor tissues is associated with poor clinical outcome. this study aimed to assess the changes in serum level of interleukin-19 in breast cancer patients in comparison with normal women and its association with the clinicopathologica...

Prognosis of metastatic breast cancer is very poor which urges the necessity to develop novel potential drug candidates. We assessed two compounds with tri-aryl structures (A and B) for their potency to reduce primary breast tumor growth and lung metastasis in 4T1 mice model. MTT assay, 4T1 mammary mouse model and immunohistochemistry experiments were used in this study. In vitro results exhibi...

Elmira Ebrahimi, Kimia Ghaffari, Mehrdad Hashemi, Reza Shirkoohi,

Background: Baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5) gene is an inhibitor of apoptosis that expresses in human embryonic tissues but it is absent in most healthy adult tissues. The copy number of BIRC5 has been indicated to be highly increased in tumor tissues; however, its association with the age of onset in breast cancer is not well understood. Methods: Forty tumor tiss...

Abbas Ghaderi Abdolkarim Sheikhi, Abdollah Jafarzadeh, Ali-Reza Farsinejad Arezu Khosravimashizi, Hamid Daneshvar, Kayhan Minaee, Maryam Nemati, Mohammad Mehdi Mohammadi

Objective(s):IL-12 as an anti-tumor cytokine and IL-33 a novel identified cytokine with both pro- or anti-tumor activities, play important roles in response against tumor cells. Our aim was to evaluate the IL-12 and IL-33 levels and single nucleotide polymorphisms (SNP) in their genes in patients with breast cancer. Materials and Methods:Blood samples were collected from 100 patients with breas...

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