CASE REPORT A 75-year-old man presents for routine follow-up examination 6 years after uncomplicated primary trabeculectomy with a 2minute intraoperative application of mitomycin C (MMC, 0.4mm/ mL). Although progression had occurred when the intraocular pressure (IOP) was in the mid teens, the visual fields have remained stable since filtration surgery was performed. The IOP is 8mm Hg and a lar...

The morphology of a bleb and its changes are critical to the amoeboid migration cell. By releasing bonds between membrane cortex cell, formation can be observed experimentally, but mechanism that affects size shape during requires further study. In this study, by adapting governing equations discrete two-dimensional fluid–solid coupling model recommended Strychalski Guy [2013 “A computational f...

PURPOSE To report a case of subconjunctival air leakage from the anterior chamber (AC) into a trabeculectomy bleb after Descemet's stripping automated endothelial keratoplasty (DSAEK). METHODS An 89 year-old woman with a previous history of primary open angle glaucoma in her left eye and previous trabeculectomy with mitomycin C had DSAEK on the patient's left eye in order to treat her endothe...

We study the nucleation of blebs, i.e., protrusions arising from a local detachment of the membrane from the cortex of a cell. Based on a simple model of elastic linkers with force-dependent kinetics, we show that bleb nucleation is governed by membrane peeling. By this mechanism, the growth or shrinkage of a detached membrane patch is completely determined by the linker kinetics, regardless of...

This case report illustrates the use of ExPRESS mini-shunt in a pediatric glaucoma patient. We describe the management of steroid-induced glaucoma with ExPRESS mini-shunt in a 9-year-old boy with allergic keratoconjunctivitis. The intraocular pressure of both of his eyes was uncontrolled with medical and laser treatment. Both eyes were treated with ExPRESS mini-shunt and mitomycin-C. Transient ...

Tumor cells rely upon membrane pliancy to escape primary lesions and invade secondary metastatic sites. This process relies upon localized assembly and disassembly cycles of F-actin that support and underlie the plasma membrane. Dynamic actin generates both spear-like and bleb structures respectively characterizing mesenchymal and amoeboid motility programs utilized by metastatic cells in three...

Hypotony maculopathy is a sight-threatening complication after trabeculectomy. We report on a 34-year-old man with juvenile open-angle glaucoma and high myopia, who developed hypotony maculopathy 14 years after trabeculectomy without bleb leak. This represents the longest known period from trabeculectomy to the development of hypotony maculopathy without bleb leak. The possible mechanisms for t...

Purpose: To report two patients with spontaneous scleral perforation and bleb formation associated with Marfan syndrome (MFS); which one of them also showed bilateral optic nerve dural ectasia. Case reports: An 11-year-old girl was referred with progressive myopia. Past medical history was negative. Slit-lamp examination revealed bilateral scleral thinning and perforation with bleb formation, s...

Abetract. Successful glaucoma filtering surgery is characterized by the passage of aqueous humor from the anterior chamber to the subconjunctival space, which results in the formation of a filtering bleb. Aqueous in the subconjunctival space may then exit by multiple pathways. Bleb failure most often results from fibroblast proliferation and subconjunctival fibrosis. Factors associated with an ...

A 19-year old female with blue rubber bleb nevus syndrome. Endoscopic laser photocoagulation and surgical resection of gastrointestinal angiomata. cerebellum: a case report and review of the literature. 39. Hofhuis WJD, Orange AP, Bouquet J, et al. Blue rubber blue nevus syndrome: report of a case with consumption coagulopathy complicated by manifest thromboses. A case report: pregnancy complic...