The kinase Aurora-A (Aur-A), which is enriched at centrosomes, is required for centrosome maturation and accurate chromosome segregation, and recent work implicates centrosomes as sites where the earliest activation of cyclin B1-cdc2 occurs. Here, we have used Xenopus egg extracts to investigate Aur-A's contribution to cell cycle progression and spindle morphology in the presence or absence of ...

I begin by outlining some restrictive conditions on linguistic variation. I programmatically suggest that syntactic structure is completely invariant and that variation is strictly limited to morphophonological properties of (functional) heads. With this background, I explore a strongly reductionist program according to which syntactic properties are licensed by one of two mechanisms: spec/head...

The idea that the verb phrase is a layered constituent has been around in the literature for some time, e. shell theory plays an important role as well. In this paper I will argue that a particular interpretation of shell theory may provide insight into long standing problems such as the nature of syntactic ergativity and the structure of psychological verbs. Let us consider a VP–structure with...

Bipolarity has not been much exploited in the spatial domain yet, although it has many features to manage imprecise and incomplete information that could be interesting in this domain. This paper is a first step to address this issue, and we propose to define mathematical morphology operations on bipolar fuzzy sets (or equivalently interval valued fuzzy sets or intuitionistic fuzzy sets).

This paper surveys various areas in information engineering where an explicit handling of positive and negative sides of information is appropriate. Three forms of bipolarity are laid bare. They can be instrumental in logical representations of incompleteness, rule representation and extraction, argumentation, and decision analysis.

Gradual semantics are now well-studied in the computational argumentation literature. In this paper, we argue that gradual can handle both bipolarity (e.g. attacks and supports) sets of attacking arguments (i.e. several together an argument) might be useful some contexts. We define formal framework properties for such semantics. proceed by adapting, studying implementing three well-known from b...

Epidemiological studies have shown that arsenic exposure during early embryogenesis can cause reduced weight gain and neurological deficits later on in life. In addition, in vitro and in vivo studies have indicated that arsenic suppresses neurogenesis and myogenesis. The exact mechanism of how arsenic causes these undesired developmental outcomes is poorly understood, however both skeletal musc...