Childhood tuberculosis is common in our community. The diagnosis in most cases is still based on clinical evidence alone. The present study was designed to study clinical profile, laboratory investigations and outcome of pediatric tuberculosis. A prospective study was conducted among the children admitted in Nepal Medical College from April 2007 to March 2011. The prevalence of tuberculosis was...

In the individuals previously uninfected by M.tuberculosis, about 2 to 4 weeks after the vaccination, erythema around an area of induration appears. Approximately at the site of prick of injection a nodule shows up. Within 3 to 10 days time, it softens giving rise to a pustule. Bursting of the pustule in about 2 to 5 days after its appearance results in an ulcer 4 to 8 mm in size. This painless...

Tuberculosis (TB) continues to be one of the most devastating and widespread infections in the world.11% of the cases occur in children causing morbidity and mortality worldwide. Methodology: An observational study was conducted among paediatric patients registered under Revised National Tuberculosis Control Programme (RNTCP) in Bangalore to know their sociodemographic and disease profile from ...

INTRODUCTION Jailed populations exhibit high rates of tuberculosis (TB) infection and active disease. METHODS A cross-sectional study was performed to estimate the prevalence of latent and active TB and to identify factors associated with latent infection in inmates. RESULTS The prevalence of latent TB was 49%, and the prevalence of active TB was 0.4%. The presence of a Bacille Calmette-Gué...

Background: Thermal stability (TS) is a part of the BCG vaccine characterization by which the consistency of process in BCG vaccine production could be confirmed. To enhance the TS of the vaccine, some prevalent stabilizers in different concentrations were added to the final formulation of BCG bulk prior to Freeze-drying process. We found a formulation more effective than the current stabilizer...

We report two infants who presented with inflammatory thigh swelling in first 6 months of life. BCG scar was seen over left upper arm in both. Mantoux test, chest X-ray and family screening were normal in both infants. Ultrasonography confirmed an intramuscular abscess in one child and subcutaneous abscess in the others. Histopathology showed granulomatous inflammation with caseous necrosis sug...

History: A seven-month-old, developmentally normal girl – born at term with birth weight of 2.5 kg to a nonconsanguineously married couple – presented with fever and rash for 11⁄2 months. The illness started with generalized erythematous, maculopapular rash involving the flexural areas, scalp and trunk, along with intermittent fever. The rash subsided over 15 days leaving behind a dry, scaly sk...

Background: Although the efficacy of Bacillus Calmette-Guerin (BCG) vaccine in the prevention of tuberculosis has been noted consistently, the use of BCG vaccine is not without risk. In this study we aimed to evaluate immunologically, children with complication of BCG vaccination in North of Iran.Materials and Methods: This case-control study began in 30 Jan 2013 and was completed in 2 Jul 2015...

background: although the efficacy of bacillus calmette-guerin (bcg) vaccine in the prevention of tuberculosis has been noted consistently, the use of bcg vaccine is not without risk. in this study we aimed to evaluate immunologically, children with complication of bcg vaccination in north of iran.materials and methods: this case-control study began in 30 jan 2013 and was completed in 2 jul 2015...