non-steroidal anti-inflammatory drugs (nsaids) have shown antibacterial activity in some recent studies. the aim of this study was to evaluate the antibacterial effect of diclofenac against enterococcus faecalis (e. faecalis) as a resistant endodontic bacterium in comparison with ibuprofen, calcium hydroxide and amoxicillin.the antibacterial activity of materials was evaluated using agar diffus...

background silver has been used from ancient times by humans, and recently nanoparticles of silver have been used in many aspects of human life including as a potent antibacterial agent. objectives in the current study a completely green method to prepare silver nanoparticles is reported. two types of starches (potato and corn starches) were used to produce and stabilize silver nanoparticles. a...

conclusions due to the variable nature of antibiotic susceptibility patterns and etiological agents of septicemia, continual assessment of the most frequent pathogens associated with bloodstream infections and detection of their sensitivity patterns to locally available antibiotics seem to be reasonable measures. results from a total of 491 blood cultures, 74 (15.1%) samples were detected as po...

patients and methods sixty children aged between 2 and 12 years, and scheduled for on-pump surgery due to a congenital heart disease were randomly assigned into two groups. oral midazolam (0.5 mg/kg up to 15 mg per patient) and dexmedetomidine (2 µg/kg) were administered 45 minutes pre-anesthesia. children’s anxiety, mask acceptance behavior, hemodynamic measures, and cardiopulmonary outcomes w...

background: to investigate the prevalence of antibiotic usage in children aged <5 years with acute respiratory tract illness (arti) in iran. materials and methods: data were collected from a national health survey conducted in 2010 (iran’s multiple indicator demographic and health survey). participants of this cross-sectional study were selected by multistage stratifi ed cluster-random sampling...

background: listeria monocytogenes is an important gram-positive disease-causing bacterium existing in milk and dairy products. inhibitory effects of mentha pulegium essential oil at concentrations of 0.03, 0.015, and 0.0075% on growth of l. monocytogenes were studied in iranian white cheese during 60 days of storage. methods: essential oil of m. pulegium plant, collected from north of iran, wa...

the urgent need of neuraminidase inhibitors (ni) has provided an impetus for understanding the structure requisite at molecular level. our search for selective inhibitors of neuraminidase has led to the identification of pharmacophoric requirements at various positions around acyl thiourea pharmacophore. the main objective of present study is to develop selective ni, with least toxicity and dru...

Multipurpose technologies that simultaneously protect from sexually transmitted infections and unintended pregnancy are urgently needed. Pod-intravaginal rings (IVRs) formulated with the antiretroviral agents (ARVs) tenofovir, nevirapine, and saquinavir and the contraceptives etonogestrel and estradiol were evaluated in sheep. Steady-state concentrations were maintained for 28 days with control...

BACKGROUND Highly active antiretroviral therapy (HAART) has improved survival for persons living with human immunodeficiency virus (HIV) infection. However, effective therapy requires high levels of adherence over extended periods of time. Previous studies suggest that patients receiving long-term medication are at risk for unintended medication discrepancies at the time of hospital admission. ...

Anti-TNF-alpha is now established as a major player in the treatment of Crohn's disease, however the use of anti-TNF-alpha therapy in patients concomitantly having HIV infection and Crohn's disease is a relatively unexplored subject. There is generally some apprehension and anxiety to use infliximab in patients with HIV. One case has been reported in literature of usage of anti-TNF-alpha in HIV...