BACKGROUND AND PURPOSE Tourniquet application is still a common practice in total knee arthroplasty (TKA) surgery despite being associated with several adverse effects. We evaluated the effects of tourniquet use on functional and clinical outcome and on knee range of motion (ROM). PATIENTS AND METHODS 70 patients who underwent TKA were randomized into a tourniquet group (n = 35) and a non-tou...

BACKGROUND Surgical removal of impacted lower third molars is a common oral surgical procedure, generally followed by moderate to severe postoperative pain. Transdermal drug delivery as a concept offers interesting possibilities for postoperative pain control. The aim of this study was to evaluate the efficacy of transdermal system with fentanyl in relieving pain following impacted lower third ...

AIM Combined analgesic regimens produce sufficient analgesia by additive or synergistic effects, and reduce the total dose of analgesics and minimise adverse effects. We investigated the metamizole, paracetamol and morphine combination with respect to postoperative pain treatment in lumbar disc surgery. MATERIAL AND METHODS After Ethics Committee approval and informed consent, 63 patients wer...

INTRODUCTION Gabapentin has demonstrated analgesic effects in clinical trials as a preemptive analgesic and in acute postoperative pain management. This study was conducted to evaluate whether the pre-emptive use of gabapentin could reduce postoperative pain and morphine consumption in patients after lower extremity orthopaedic surgery. METHODS 70 ASA I and II patients were randomly assigned ...

BACKGROUND Women undergoing cesarean (CS) delivery present a unique set of challenges to the anesthetist in terms of postoperative pain management. This study was conducted to compare the analgesic efficacy of intrathecal buprenorphine (ITB) with ultrasound-guided transversus abdominis plane (TAP) block in post-CS delivery pain. METHODOLOGY A prospective randomized comparative study of sixty ...

BACKGROUND Multimodal analgesia featuring peripheral nerve blocks decreases postoperative pain for patients undergoing primary total knee arthroplasty (TKA). Many anesthesiologists and surgeons advocate for the use of adductor canal blocks (ACBs) for analgesia, which result in less weakness compared to femoral nerve blocks. Few data exist to guide analgesic management in total knee revision (TK...

Without mentioning chronic pain, acute postoperative pain has been regarded as a matter of great concern to patients as well as physicians. The 'Pain as the Fifth Vital Sign' initiative may have helped make its control of primary importance in the perioperative management of surgical patients [1]. Extensive literature has demonstrated the benefits of effective postoperative pain control includi...

M. Segasothy, Department of Medicine, University Kebangsaan Malaysia, Jalan Raja Muda, Kuala Lumpur 50300 (Malaysia) Dear Sir, Analgesic nephropathy has most commonly been attributed to the excessive consumption of analgesic compounds commonly containing aspirin, phenacetin and caffeine. Occasional examples of renal papillary necrosis with individual analgesics such as aspirin, indomethacin or ...

BACKGROUND Preemptive analgesia is considered an alternative for treating the postsurgical pain of third molar removal. The aim of this study was to evaluate the preemptive analgesic efficacy of oral ketorolac versus intramuscular tramadol after a mandibular third molar surgery. MATERIAL AND METHODS A parallel, double-blind, randomized, placebo-controlled clinical trial was carried out. Thirt...

BACKGROUND Epidural administration of dexamethasone might reduce postoperative pain in adults. We evaluated whether a caudal block of 0.1 mg kg(-1) dexamethasone combined with ropivacaine improves analgesic efficacy in children undergoing day-case orchiopexy. METHODS This randomized, double-blind study included 80 children aged 6 months to 5 yr who underwent day-case, unilateral orchiopexy. P...