Background: To evaluate the association of increased fetal nuchal translucency( NT) and adverse pregnancy outcomes. Materials and Methods: In a prospective study, 2221 women who were conceived after Assisted Conception were investigated by sonography independent of multiplicity between 11 and 13 weeks' gestation. We performed 2899 NT examinations during the study period(21 March 2010 to 21...

objective: to investigate the clinical advantage of several prognostic factors for predicting preterm delivery. materials and methods: eighty and six patients with a singleton pregnancy admitted to vali-asr hospital underwent genetic amniocentesis between the 15th and 23th weeks were included in this study. maternal serum c-reactive protein (crp), transvaginal sonographic measurement of cervica...

To gain insight into how pregnant women experience serum screening for Down syndrome, we sent questionnaires to two groups of relevant subjects in the north of the Netherlands. The questionnaires addressed the following issues: decision-making process, knowledge and opinions. Questionnaire A was sent to women of 36 years of age and older (n=99) (group A) who were all 20 to 36 weeks pregnant at ...

Previous event-related potential (ERP) studies have revealed that faces and words show a robust difference in the lateralization of their N170. The present study investigated the development of this differential lateralization in school-age boys. We assessed the potential role of fetal testosterone (FT) level as a factor biasing the prenatal development of lateralization, and the role of readin...

The Atraumatic Amniocentesis needle is manufactured by TSK Laboratory, Japan (Tochigi-Shi, Tochigi-Keri, 328 Japan). It is a 22 gauge, 90 mm needle. It has a pencil point tip with two circular holes at the tip. It is composed of a stainless steel AISI 304 with a polycarbonate hub. OD – 0.70±0.01 mm. ID – 0.40±0. 01 mm. Obturator length – 109.5±2 mm. OD of the obturator – 0.35±0.01 mm. Location ...

OBJECTIVE To assess the value of second trimester genetic ultrasound for screening of Down syndrome conducted at Srinagarind Hospital, Khon Kaen, Thailand. MATERIAL AND METHOD The present study sample comprised of 4,033 pregnant women at high risk forfetal chromosomal abnormality, from 17th to 23th week, who had performed second trimester genetic ultrasound before genetic amniocentesis betwee...

Rapid prenatal diagnostic tests are now increasingly popular, either as a stand-alone test or associated with conventional karyotype. Their main advantages are maternal anxiety relief and low cost. However, the results are available in more than 48 hours from amniocentesis. We present a rapid fluorescence in situ hybridization (FISH) technique, modified to give prenatal diagnostic results in th...

OBJECTIVES To describe the experiences of a small group of women who had positive results after serum screening for Down's syndrome. DESIGN Semistructured telephone interviews and correspondence with women after a positive screening result (four women) negative amniocentesis results (eight), or termination of a pregnancy with a confirmed abnormality (eight). SUBJECTS 20 women who contacted ...

OBJECTIVE Cell-free DNA (cfDNA) offers highly accurate noninvasive screening for Down syndrome. Incorporating it into routine care is complicated. We present our experience implementing a novel program for cfDNA screening, emphasizing patient education, genetic counseling, and resource management. STUDY DESIGN Beginning in January 2013, we initiated a new patient care model in which high-risk...