نتایج جستجو برای: alport syndrorme
تعداد نتایج: 843 فیلتر نتایج به سال:
The clinical implications of thin basement membrane nephropathy (TBMN) in renal transplantation must be considered from the perspectives of both the allograft recipient and the donor. Most individuals with TBMN have a benign course, but some develop end-stage renal failure (ESRF) and undergo transplantation. ESRF in patients with TBMN often results from the presence of additional glomerular or ...
Identification of a Mutation in COL4A5 Causative for X-linked Alport Syndrome in the Domestic Dog and Analysis of Gene Expression in the Kidneys of Affected and Nonaffected Siblings. (December 2003) Melissa Luanne Cox, B.Sc., Dalhousie University Chair of Advisory Committee: Dr. Keith E. Murphy The domestic dog, Canis lupus familiaris, plays many roles in the lives of humans. Additionally, the ...
INTRODUCTION Alport Syndrome has a prevalence of 1 case per 5,000 people and 85% of patients have the X-linked form, where affected males develop renal failure and usually have high-tone sensorineural deafness by age 20. The main abnormality is deficient synthesis of type IV collagen, the main component of basement membranes. Common ocular abnormalities of this syndrome consist of dot-and-fleck...
This report describes the renal pathology in three siblings with hereditary nephritis. All three cases showed combined features of chronic glomerulonephritis, pyelonephritis, and interstitial nephritis. Foam cells were seen in only one case. These findings support the contention of Krickstein, Gloor, and Balogh (1966) that the renal changes in hereditary nephritis are those of a mixed nephritis.
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