Prof. Dr. K. Metze, Department of Pathology, Faculty of Medicine, POB 6111, State University of Campinas, BR 13081 Campinas-SP (Brazil) Nucleolar organizer regions (AgNORs) have been widely studied in a variety of neoplasias, but only a few investigations deal with AgNORs in blood diseases. We therefore read with interest the study by Nakamura et al. [1] on AgNORs in acute leuke-mias, and would...

background: the health risks of crack cocaine smoking on the oral mucosa has not been widely researched and documented. objective: the purpose of this study was to analyze the proliferative activity of oral epithelial cells exposed to crack cocaine smoke using silver nucleolar organizer region (agnor) staining. methods: oral smears were collected from clinically normal-appearing buccal mucosa b...

Aims-To study correlations between the pattern of silver stained nucleolar organiser regions (AgNORs) in chronic lymphocytic leukaemia (CLL) and parameters of tumour kinetics. To investigate whether quantitation of the AgNOR pattern can be used to discriminate between patients with stable and progressive disease.Methods-Peripheral blood smears from 48 patients with CLL, classified as having eit...

Background: It is well known that tobacco smoke causes cellular proliferation and chronic obstructive pulmonary disease (COPD), but changes in buccal mucosa cells in smokers and COPD patients remains unknown. Aims: The aim of this study is twofold: (i) to assess the effect of smoking on cellular proliferative activity of buccal mucosa in healthy smokers and in smoking COPD patients (ii) to dete...

Aydınlatma, modern tavuk yetiştiriciliğinde, üreme, büyüme, vücut sıcaklığı, yem tüketimi ve sindirim olayları da dahil olmak üzere birçok fizyolojik süreci etkileyen metabolik olaylarda belirleyici rol oynayan önemli unsurlardan biridir. Aydınlatmaya bağlı olarak oluşan değişiklikler, sinir sistemi endokrin sistemin görev aldığı olaylar sonucu meydana gelmektedir. Purkinje hücreleri, merkezi s...

Objectives: To compare the different histological variants of ameloblastoma in terms of proliferative activity, using the histochemical method of AgNORs and to grade different variants of ameloblastoma. Methods: It was a cross sectional study of 50 surgical specimens, collected by non probability convenient sampling technique, of ameloblastoma were selected from different hospitals of Lahore (M...

AIMS To investigate the relation between the numbers of interphase silver stained nucleolar organiser regions (AgNORs) and immunolabelling with the monoclonal antibody PC10, which demonstrates proliferating nuclei by reacting with proliferating cell nuclear antigen (PCNA). METHODS The established sequential technique for the demonstration of interphase AgNORs and of antigens in paraffin wax s...