The presence of immunoglobulin E (IgE) antibodies was determined by using the immunosorbent-agglutination assay (ISAGA) with 611 serum samples from patients with different clinical conditions to evaluate its value for the serodiagnosis of acute Toxoplasma gondii infection. By analyzing 43 consecutively drawn serum samples from 10 pregnant women who seroconverted, we could show that specific IgE...

BACKGROUND The different laboratory methods used in the diagnosis of congenital toxoplasmosis have variable sensitivity and specificity. There is no evidence to prove that maternal treatment reduces the risk of fetal infection. The purpose of this study was to assess methods for the confirmation of congenital toxoplasmosis after maternal treatment with spiramycin during pregnancy, and to evalua...

A goal of the current study was to evaluate serological applications of Toxoplasma gondii GRA2 and rhoptry protein 1 (ROP1) antigens. Soluble recombinant GRA2 and ROP1 antigens as fusion proteins containing six histidyl residues at the N and C terminals were obtained using an Escherichia coli expression system. Purification by one-step metal affinity chromatography allowed recovery of milligram...

introduction : toxoplasmosis, caused by toxoplasma gondii, is a protozoan parasitic infection distributed worldwide. early infection by this protozoa can lead to abortion and congenital toxoplasmosis in pregnant women. this study was conducted to determine the seroprevalence of t. gondii infection among pregnant women referring to shahid akbar abadi hospital, tehran, iran during 2010-2013. meth...

A unique co-infection with Toxoplasma gondii and Capillaria hepatica is reported in a semi-freeliving ring-tailed lemur (Lemur catta). In this case acute toxoplasmosis, characterised by severe necrotising inflammation in different organs, was the leading cause of death, whilst accompanying chronic capillariasis was regarded as a predisposing factor. A concise description of both disease manifes...

Introduction: Acute Toxoplasmosis is more critical in immunocompromised patients with cancer. The present study was conducted to investigate the anti-Toxoplasma gondi antibodies and assess the toxoplasmosis risk in women with breast masses in western of Iran in 2012. This research was done as a case-control study on women who referred to the treatment centers in cities of Kermanshah and Ilam ...

The aim of this study to evaluate the expression Programmed cell death-1 (PD-1), TGF- ß, and IL-10 in placental tissue aborted women correlation with Toxoplasma.gondii (T. gondii) these cytokines each other toxoplasmosis, during an abortion. samples have been processed used for immunohistochemistry PDL-1, IL-10, TGF-β. There was increase TGF-β, infected T.gondii, results showed that residence p...

The monitoring of 290 pregnant women with suspicion of acute toxoplasmosis attended by Public Health Services is discussed. In 69% a single test (Elisa-IgM) led to the treatment. Of 112 treated, the system did not offer any drug to 24%. In 12.1% there was a progressive increase of IgM and IgG. In 48.2% the treatment was begun thirty days after the laboratorial diagnosis.

Focal encephalitis occurred in a girl with activation of chorioretinitis which on clinical and serological grounds was taken to be caused by toxoplasma. The encephalitis and acute ocular inflammation resolved with treatment with pyrimethamine and sulphadiazine. This is presumably an example of reactivation of congenital cerebral toxoplasmosis.